Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0308 and Rv0309 are separated by 101 nucleotidesRv0309 and Rv0310c are separated by 69 nucleotidesRv0310c and Rv0311 are separated by 23 nucleotidesRv0311 and Rv0312 are separated by 154 nucleotides Rv0308: Rv0308 - Probable conserved integral membrane protein, at 377,113 to 377,829 Rv0308 Rv0309: Rv0309 - Possible conserved exported protein, at 377,931 to 378,587 Rv0309 Rv0310c: Rv0310c - Conserved protein, at 378,657 to 379,148 Rv0310c Rv0311: Rv0311 - Unknown protein, at 379,172 to 380,401 Rv0311 Rv0312: Rv0312 - Conserved hypothetical proline and threonine rich protein, at 380,556 to 382,418 Rv0312
Group Condition Rv0308 Rv0309 Rv0310c Rv0311 Rv0312
stress 7H9 with Rifampicin 0.014 ug/mL -0.0 -1.9 -0.3 -0.3 -1.0
stress 7H9 with Rifampicin 0.014 ug/mL -0.2 -1.5 -0.0 +0.2 -1.2
stress 7H9 with Bedaquiline 0.15 ug/mL -0.2 -0.9 -0.1 -0.7 -0.5
stress 7H9 with Rifampicin 0.00045 ug/mL -0.1 -0.7 +0.4 -0.8 -0.4
stress 7H9 with Clofazimine 0.072 ug/mL +0.0 -0.9 +0.1 -0.9 +0.0
stress 7H9 with Clofazimine 0.45 ug/mL -0.0 -0.9 -0.3 +0.4 -0.8
stress 7H9 with para-aminosalicylic 0.086 ug/mL -0.1 -0.6 -1.1 +0.2 +0.1
stress 7H9 with Clofazimine 0.072 ug/mL -0.0 -1.1 -0.3 +0.2 -0.3
stress 7H9 with Rifampicin 0.00045 ug/mL -0.1 -1.0 +0.3 -0.1 -0.4
no stress control no stress control -0.6 -1.0 +1.3 -0.6 -0.3
stress 7H9 with Clofazimine 0.45 ug/mL -0.0 -0.7 +0.6 -0.5 -0.4
nitrogen source L-Alanine 10 mM (N) +0.4 -0.3 -0.5 +0.3 -0.3
stress 7H9 with Delamanid 0.236 ug/mL -0.1 -0.3 -0.6 +0.9 +0.1
carbon source D-Glucose (C) -0.2 +0.3 +0.3 -0.7 +0.2
stress 7H9 with Bedaquiline 0.15 ug/mL -0.0 -0.8 +1.0 +0.3 -0.5
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.1 -0.1 +1.0 -0.5 -0.1
stress 7H9 with Ethionamide 0.1 ug/mL +0.1 -1.1 +1.0 +0.8 -0.3
no stress control no stress control -0.2 -0.4 +0.5 +0.4 +0.2
nitrogen source L-Asparagine 10 mM (N) +0.0 -0.4 +0.6 +0.6 -0.3
stress 7H9 with Dimethyl Sulfoxide 1 vol% +0.3 -0.6 +0.4 +0.0 +0.4
no stress control no stress control -0.2 -0.5 +0.8 +0.4 +0.1
stress 7H9 with Isoniazid 0.025 ug/mL -0.0 -0.8 +1.4 +0.3 -0.2
nitrogen source L-Glutamine 10 mM (N) +0.0 -0.3 +0.4 +0.9 -0.3
carbon source Valeric 10 mM (C) +0.1 +0.3 +0.9 -0.4 +0.0
stress 7H9 with Ofloxacin 0.8 ug/mL -0.1 +0.2 +1.3 -0.5 -0.1
stress 7H9 with Ethionamide 0.1 ug/mL +0.3 -0.3 +1.6 -0.3 -0.1
stress 7H9 with Ofloxacin 0.8 ug/mL -0.2 +0.2 +1.4 -0.1 -0.1
stress 7H9 with Moxifloxacin 0.121 ug/mL -0.2 +0.2 +1.5 +0.1 -0.2
stress 7H9 with Isoniazid 0.025 ug/mL -0.0 -0.6 +1.6 +0.4 +0.1
carbon source D,L-Malic Acid 10 mM (C) -0.2 +0.3 +0.8 +0.3 +0.2
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