Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0278c and Rv0279c are separated by 249 nucleotidesRv0279c and Rv0280 are separated by 290 nucleotidesRv0280 and Rv0281 are separated by 23 nucleotidesRv0281 and Rv0282 are separated by 223 nucleotides Rv0278c: Rv0278c - PE-PGRS family protein PE_PGRS3, at 333,437 to 336,310 Rv0278c Rv0279c: Rv0279c - PE-PGRS family protein PE_PGRS4, at 336,560 to 339,073 Rv0279c Rv0280: Rv0280 - PPE family protein PPE3, at 339,364 to 340,974 Rv0280 Rv0281: Rv0281 - Possible S-adenosylmethionine-dependent methyltransferase, at 340,998 to 341,906 Rv0281 Rv0282: Rv0282 - ESX conserved component EccA3. ESX-3 type VII secretion system protein., at 342,130 to 344,025 Rv0282
Group Condition Rv0278c Rv0279c Rv0280 Rv0281 Rv0282
stress 7H9 with nitrate 4 mM -1.0 -1.2 -1.0 -1.1 N.D.
stress 7H9 with Sisomicin 0.07 mM -0.9 -1.4 -1.3 -0.5 N.D.
carbon source L-Asparagine (C) -0.5 -0.9 -1.5 -0.4 N.D.
carbon source L-Asparagine (C) -0.4 -0.7 -1.4 -0.5 N.D.
carbon source propionate (C) -0.2 -0.2 -1.8 -0.3 N.D.
no stress control no stress control -0.6 -1.2 -0.4 -0.2 N.D.
stress 7H9 with Phenazine ethosulfate 0.0137 mM -0.7 -0.7 -0.6 -0.3 N.D.
no stress control no stress control -0.4 -0.9 -0.5 +0.1 N.D.
carbon source D-Lactate 10 mM (C) +0.2 -0.4 -1.4 +0.2 N.D.
nitrogen source L-Serine 10 mM (N) +0.2 +0.1 -1.7 -0.1 N.D.
nitrogen source L-Asparagine 10 mM (N) +0.0 -0.4 -1.3 +0.4 N.D.
stress 7H9 with Ethionamide 0.1 ug/mL +0.6 +0.6 +0.2 +0.4 N.D.
no stress control no stress control +0.6 +0.5 +0.6 +0.2 N.D.
stress 7H9 with Levofloxacin 0.3 ug/mL +0.6 +0.8 +0.6 -0.2 N.D.
stress 7H9 with Zinc Pyrithione 0.00072 mM +0.7 +0.8 +0.5 +0.1 N.D.
no stress control no stress control +0.5 +0.7 +0.6 +0.4 N.D.
stress 7H9 with Irgasan 0.065 mM +0.5 +0.8 +0.6 +0.3 N.D.
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 +0.8 +0.8 +0.4 +0.4 N.D.
stress 7H9 with Linezolid 0.44 ug/mL +0.7 +0.8 +0.3 +0.6 N.D.
stress 7H9 with Ethionamide 0.1 ug/mL +0.7 +1.2 +0.7 +0.1 N.D.
stress 7H9 with Streptomycin 0.178 ug/mL +0.7 +0.9 +0.7 +0.5 N.D.
stress 7H9 with Ofloxacin 0.8 ug/mL +0.9 +0.9 +0.9 +0.4 N.D.
stress 7H9 with Levofloxacin 0.3 ug/mL +0.9 +1.4 +0.9 +0.0 N.D.
stress 7H9 with Ofloxacin 0.8 ug/mL +0.9 +1.2 +0.8 +0.5 N.D.
stress 7H9 with Isoniazid 0.025 ug/mL +0.5 +1.5 +0.6 +0.9 N.D.
stress 7H9 with Isoniazid 0.025 ug/mL +0.8 +1.1 +0.6 +1.1 N.D.
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.7 +1.2 +1.0 +1.0 N.D.
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.9 +1.2 +1.1 +0.8 N.D.
no stress control no stress control +1.1 +1.4 +0.9 +0.6 N.D.
no stress control no stress control +1.0 +1.4 +0.9 +0.7 N.D.
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