Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0262c and Rv0263c are separated by 9 nucleotidesRv0263c and Rv0264c are separated by 16 nucleotidesRv0264c and Rv0265c are separated by 95 nucleotidesRv0265c and Rv0266c are separated by 21 nucleotides Rv0262c: Rv0262c - Aminoglycoside 2'-N-acetyltransferase Aac (Aac(2')-IC), at 314,309 to 314,854 Rv0262c Rv0263c: Rv0263c - Conserved hypothetical protein, at 314,864 to 315,766 Rv0263c Rv0264c: Rv0264c - Conserved hypothetical protein, at 315,783 to 316,415 Rv0264c Rv0265c: Rv0265c - Probable periplasmic iron-transport lipoprotein, at 316,511 to 317,503 Rv0265c Rv0266c: Rv0266c - Probable 5-oxoprolinase OplA (5-oxo-L-prolinase) (pyroglutamase) (5-OPASE), at 317,525 to 321,154 Rv0266c
Group Condition Rv0262c Rv0263c Rv0264c Rv0265c Rv0266c
nitrogen source L-Valine 10 mM (N) -0.4 -0.7 -0.0 -0.2 -0.1
stress 7H9 with Rifampicin 0.014 ug/mL -0.3 -0.3 -0.0 -0.6 -0.2
nitrogen source L-Glutamic 10 mM (N) -0.5 -0.6 +0.0 -0.1 -0.1
stress 7H9 with Ethambutol 0.75 ug/mL -0.1 -0.4 +0.2 -0.2 -0.1
stress 7H9 with Pretomanid 0.213 ug/mL +0.1 +0.3 -0.1 -0.6 -0.0
stress 7H9 with Rifampicin 0.014 ug/mL -0.1 -0.3 +0.4 -0.2 -0.1
carbon source butyrate 10 mM (C) +0.3 -0.4 -0.3 -0.2 +0.3
no stress control no stress control -0.3 +0.2 -0.4 +0.2 +0.1
nitrogen source L-Glutamine 10 mM (N) -0.2 +0.3 -0.2 -0.2 +0.1
carbon source Stearic 100 uM (C) +0.3 -0.1 -0.5 -0.1 +0.2
nitrogen source L-Aspartic Acid 10 mM (N) +0.5 -0.3 -0.0 -0.2 -0.1
carbon source L-Lactate 10 mM (C) +0.3 -0.1 +0.1 -0.4 -0.1
stress 7H9 with Levofloxacin 0.3 ug/mL -0.5 -0.1 +0.4 -0.1 +0.2
carbon source D-Trehalose 10 mM (C) +0.3 +0.0 +0.3 -0.5 -0.1
nitrogen source L-Glutamic 10 mM (N) +0.6 -0.4 +0.0 -0.1 -0.1
stress 7H9 with Isoniazid 0.025 ug/mL -0.4 +0.2 +0.5 -0.0 -0.0
carbon source casaminos 1 mg/mL (C) +0.6 +0.2 -0.2 -0.2 -0.0
carbon source D-Trehalose 10 mM (C) +0.2 +0.4 +0.4 -0.3 -0.1
stress 7H9 with Ethionamide 0.1 ug/mL -0.1 +0.3 -0.2 +0.5 +0.1
carbon source propionate (C) +0.3 +0.4 -0.3 +0.4 +0.0
no stress control no stress control +0.4 +0.1 -0.2 +0.5 +0.1
stress 7H9 with Ofloxacin 0.8 ug/mL -0.1 +0.2 +0.6 +0.1 +0.1
nitrogen source Glycine 10 mM (N) -0.1 +0.5 +0.7 -0.1 +0.0
stress 7H9 with Ofloxacin 0.8 ug/mL -0.3 +0.1 +0.7 +0.3 +0.3
stress 7H9 with Isoniazid 0.025 ug/mL -0.0 +0.2 +0.5 +0.2 +0.2
no stress control no stress control +0.2 +0.2 +0.3 +0.3 -0.0
no stress control no stress control +0.2 +0.3 +0.3 +0.4 +0.1
stress 7H9 with Streptomycin 0.178 ug/mL +0.2 +0.5 +0.1 +0.4 +0.1
no stress control no stress control -0.4 +0.6 +0.6 +0.5 +0.1
stress 7H9 with Ethionamide 0.1 ug/mL +0.1 +0.5 +0.7 +0.2 +0.2
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