Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0261c and Rv0262c are separated by 140 nucleotidesRv0262c and Rv0263c are separated by 9 nucleotidesRv0263c and Rv0264c are separated by 16 nucleotidesRv0264c and Rv0265c are separated by 95 nucleotides Rv0261c: Rv0261c - Probable integral membrane nitrite extrusion protein NarK3 (nitrite facilitator), at 312,759 to 314,168 Rv0261c Rv0262c: Rv0262c - Aminoglycoside 2'-N-acetyltransferase Aac (Aac(2')-IC), at 314,309 to 314,854 Rv0262c Rv0263c: Rv0263c - Conserved hypothetical protein, at 314,864 to 315,766 Rv0263c Rv0264c: Rv0264c - Conserved hypothetical protein, at 315,783 to 316,415 Rv0264c Rv0265c: Rv0265c - Probable periplasmic iron-transport lipoprotein, at 316,511 to 317,503 Rv0265c
Group Condition Rv0261c Rv0262c Rv0263c Rv0264c Rv0265c
stress 7H9 with Levofloxacin 0.3 ug/mL -0.2 -0.3 -0.6 -0.5 -0.1
nitrogen source L-Glutamic 10 mM (N) -0.3 -0.5 -0.6 +0.0 -0.1
stress 7H9 with Ceftriaxone hemi(heptahydrate) 0.12 mM -0.4 -0.1 +0.2 -0.5 -0.4
stress 7H9 with Linezolid 0.3 ug/mL -0.1 -0.4 -0.8 -0.1 +0.2
stress 7H9 with Nickel (II) chloride 0.6 mM -0.1 -0.4 -0.0 -0.9 +0.3
stress 7H9 with Zinc Pyrithione 0.00072 mM -0.3 -0.3 -0.1 -0.5 +0.3
stress 7H9 with Sisomicin 0.07 mM +0.6 -3.4 +1.3 +1.2 -0.5
stress 7H9 with Cumene hydroperoxide 0.05 mM -0.3 -0.4 -0.0 -0.3 +0.4
carbon source D-Trehalose 10 mM (C) -0.5 +0.3 +0.0 +0.3 -0.5
carbon source cholesterol 100uM (C) -0.3 -0.3 +0.4 -0.3 +0.2
carbon source cholesterol 100uM (C) -0.4 -0.5 -0.3 +0.4 +0.4
nitrogen source Ammonium chloride 10mM (N) -0.5 -0.4 +0.2 +0.2 +0.3
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 6.5 -0.2 -0.7 +0.3 +0.4 +0.0
no stress control no stress control +0.1 +0.2 -0.5 -0.3 +0.4
no stress control no stress control -0.2 +0.7 -0.5 -0.1 +0.3
no stress control no stress control -0.3 +0.3 -0.0 -0.3 +0.5
pH pH 4.5 +0.2 -0.4 +0.6 +0.1 -0.4
pH pH 4.5 +0.1 -0.4 +0.5 +0.6 -0.6
carbon source D-Trehalose 10 mM (C) -0.3 +0.2 +0.4 +0.4 -0.3
stress 7H9 with Ofloxacin 0.8 ug/mL -0.2 -0.3 +0.1 +0.7 +0.3
no stress control no stress control -0.3 +0.4 +0.1 -0.2 +0.5
stress 7H9 with Dicloxacillin 0.0069 mM -0.0 -0.6 +0.4 +0.4 +0.5
stress 7H9 with Nickel (II) chloride 0.6 mM +0.1 +0.8 -0.2 -0.3 +0.2
no stress control no stress control -0.1 -0.3 +0.4 +0.3 +0.4
carbon source propionate (C) -0.1 +0.3 +0.4 -0.3 +0.4
stress 7H9 with Streptomycin 0.178 ug/mL -0.4 +0.2 +0.5 +0.1 +0.4
stress 7H9 with Geneticin G418 0.35 mM -0.1 -0.4 +0.1 +0.4 +0.8
stress 7H9 with Sisomicin 0.07 mM +1.0 -2.1 +1.0 +1.0 +0.1
no stress control no stress control -0.1 -0.4 +0.5 +0.6 +0.5
stress 7H9 with Ethionamide 0.1 ug/mL -0.1 +0.2 +0.4 +0.7 +0.2
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