Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0206c and Rv0207c are separated by 65 nucleotidesRv0207c and Rv0208c are separated by 2 nucleotidesRv0208c and Rv0209 are separated by 131 nucleotidesRv0209 and Rv0210 overlap by 4 nucleotides Rv0206c: Rv0206c - Possible conserved transmembrane transport protein MmpL3, at 244,484 to 247,318 Rv0206c Rv0207c: Rv0207c - Conserved hypothetical protein, at 247,384 to 248,112 Rv0207c Rv0208c: Rv0208c - Hypothetical methlytransferase (methylase), at 248,115 to 248,906 Rv0208c Rv0209: Rv0209 - Hypothetical protein, at 249,038 to 250,123 Rv0209 Rv0210: Rv0210 - Hypothetical protein, at 250,120 to 251,598 Rv0210
Group Condition Rv0206c Rv0207c Rv0208c Rv0209 Rv0210
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM N.D. -0.5 -0.5 -0.8 -0.2
stress 7H9 with hypochlorite 0.4 vol% N.D. -0.6 -1.6 +0.1 +0.1
stress 7H9 with Moxifloxacin 0.121 ug/mL N.D. -1.3 -0.1 -0.6 +0.1
stress 7H9 with 2-bromo-2-nitro-1,3-propanediol 0.1 mM N.D. -0.7 -0.6 -0.5 -0.1
stress 7H9 with methylglyoxal 1.2 mM N.D. -0.3 -1.3 +0.0 -0.1
stress 7H9 with copper (II) chloride 0.08 mM N.D. -1.1 +0.2 -0.6 -0.1
stress 7H9 with methylglyoxal 1.2 mM N.D. -0.3 -1.2 -0.1 +0.2
stress 7H9 with 2,4-Dinitrophenol 0.1503 mM N.D. -0.7 -0.8 +0.3 +0.1
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 N.D. -0.7 -0.8 +0.4 +0.1
no stress control no stress control N.D. -1.3 +0.3 -0.2 +0.2
stress 7H9 with Nickel (II) chloride 0.6 mM N.D. +0.4 -1.7 +0.2 +0.2
stress 7H9 with Nickel (II) chloride 0.6 mM N.D. +0.7 -1.7 +0.3 -0.1
pH 7H9 pH 5.5 N.D. +0.4 -0.9 -0.4 +0.1
stress 7H9 with Isoniazid 0.025 ug/mL N.D. -0.5 +0.3 -0.7 +0.2
stress 7H9 with Hydrogen peroxide 2.5 mM; pH 5.5 N.D. +0.1 -1.2 +0.9 -0.5
pH pH 4.5 N.D. -0.1 -0.8 +0.6 -0.2
stress 7H9 with Formaldehyde 0.23 mM N.D. +0.3 -1.4 +0.2 +0.4
stress 7H9 with Clofazimine 0.45 ug/mL N.D. +0.7 -0.7 -0.4 -0.1
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. -0.8 +0.4 -0.5 +0.5
stress 7H9 with Ofloxacin 0.8 ug/mL N.D. -1.0 +0.8 -0.4 +0.4
nitrogen source L-Serine 10 mM (N) N.D. +0.2 -0.7 +0.6 -0.1
no stress control no stress control N.D. +0.8 -0.8 +0.0 +0.1
stress 7H9 with Antimycin A 0.0186 mM N.D. +0.7 +0.2 -0.8 +0.1
no stress control no stress control N.D. +0.9 -1.0 +0.4 +0.1
stress 7H9 with Ciprofloxacin Hydrochloride 0.0012 mM N.D. +0.5 +0.5 -0.6 -0.0
stress 7H9 with Sisomicin 0.07 mM N.D. -0.3 +1.1 -0.8 +0.5
stress 7H9 with copper (II) chloride 0.08 mM N.D. -0.6 +0.4 +0.7 +0.0
no stress control no stress control N.D. -0.5 +0.5 +0.6 +0.2
stress 7H9 with Hygromycin B 0.0095 mM N.D. +1.0 -0.5 +0.2 +0.1
nitrogen source Urea 10mM (N) N.D. +1.2 +0.4 +0.3 -0.1
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