Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0197 and Rv0198c overlap by 4 nucleotidesRv0198c and Rv0199 are separated by 42 nucleotidesRv0199 and Rv0200 overlap by 4 nucleotidesRv0200 and Rv0201c overlap by 4 nucleotides Rv0197: Rv0197 - Possible oxidoreductase, at 232,231 to 234,519 Rv0197 Rv0198c: Rv0198c - Probable zinc metalloprotease Zmp1, at 234,516 to 236,507 Rv0198c Rv0199: Rv0199 - Probable conserved membrane protein, at 236,550 to 237,209 Rv0199 Rv0200: Rv0200 - Possible conserved transmembrane protein, at 237,206 to 237,895 Rv0200 Rv0201c: Rv0201c - Conserved protein, at 237,892 to 238,395 Rv0201c
Group Condition Rv0197 Rv0198c Rv0199 Rv0200 Rv0201c
stress 7H9 with Isoniazid 0.025 ug/mL -0.3 +0.2 +0.2 -2.0 -1.7
stress 7H9 with Phenazine methosulfate 0.0054 mM -0.2 -0.0 -1.4 -1.1 -1.0
carbon source Stearic 100 uM (C) +0.2 -0.0 -1.8 -2.1 +0.3
carbon source heptadecanoic 250 uM (C) +0.2 +0.2 -1.7 -2.4 +0.3
nitrogen source L-Asparagine 10 mM (N) +0.1 -0.2 +0.1 -1.7 -1.6
stress 7H9 with Phenazine methosulfate 0.0054 mM -0.3 -0.0 -0.8 -2.7 +0.4
nitrogen source Urea 10mM (N) -0.3 +0.1 -1.2 -1.6 -0.2
carbon source cholesterol 100uM (C) -0.0 -0.0 -0.8 -2.3 -0.1
no stress control no stress control -0.4 +0.0 -0.8 -0.3 -1.7
stress 7H9 with Bedaquiline 0.15 ug/mL +0.1 +0.2 -1.4 -1.4 -0.7
stress 7H9 with Bedaquiline 0.15 ug/mL +0.2 +0.1 -1.9 -1.6 +0.2
stress 7H9 with copper (II) chloride 0.08 mM +0.0 -0.3 -0.6 -1.9 -0.3
stress 7H9 with Ethionamide 0.1 ug/mL -0.1 -0.1 -0.4 -1.7 -0.7
stress 7H9 with nitrite 2.5 mM -0.4 -0.0 +0.1 -1.6 -1.0
stress 7H9 with copper (II) chloride 0.08 mM -0.3 -0.5 -0.5 -1.1 -0.5
stress 7H9 with Pyrazinamide 50 ug/mL; pH 5.5 +0.2 -0.1 -1.1 -1.5 -0.4
stress 7H9 with Dodecyl Sulfate 0.02 vol% -0.2 +0.1 -0.3 -1.9 -0.5
no stress control no stress control -0.0 -0.1 -0.9 -0.9 -1.0
carbon source Glycerol (C) +0.0 -0.2 -0.4 -2.1 -0.1
stress 7H9 with Amikacin di2 ug/mL +0.2 -0.2 -0.8 -0.0 -1.6
stress 7H9 with Antimycin A 0.0186 mM +0.2 -0.0 -0.7 -1.8 -0.2
nitrogen source Ammonium chloride 10mM (N) +0.4 -0.1 -0.6 -0.4 -1.7
carbon source heptadecanoic 250 uM (C) +0.3 -0.2 -0.9 -1.8 +0.3
carbon source Stearic 100 uM (C) +0.1 -0.2 -1.3 -1.4 +0.5
carbon source L-Aspartic Acid (C) -0.1 +0.1 +0.3 -0.3 -2.1
no stress control no stress control -0.4 -0.2 -0.8 -1.0 +0.7
stress 7H9 with Linezolid 0.3 ug/mL -0.2 -0.1 -0.6 -1.3 +0.7
stress 7H9 with Econazole nitrate salt 0.0082 mM -0.2 +0.5 +0.5 -0.8 -0.7
carbon source oleate 200uM (C) -0.3 -0.1 +0.8 +1.5 -1.1
carbon source oleate 200uM (C) +0.0 +0.2 +1.0 +1.2 -1.2
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