Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0169 and Rv0170 overlap by 4 nucleotidesRv0170 and Rv0171 overlap by 4 nucleotidesRv0171 and Rv0172 overlap by 4 nucleotidesRv0172 and Rv0173 overlap by 4 nucleotides Rv0169: Rv0169 - Mce-family protein Mce1A, at 198,534 to 199,898 Rv0169 Rv0170: Rv0170 - Mce-family protein Mce1B, at 199,895 to 200,935 Rv0170 Rv0171: Rv0171 - Mce-family protein Mce1C, at 200,932 to 202,479 Rv0171 Rv0172: Rv0172 - Mce-family protein Mce1D, at 202,476 to 204,068 Rv0172 Rv0173: Rv0173 - Possible Mce-family lipoprotein LprK (Mce-family lipoprotein Mce1E), at 204,065 to 205,237 Rv0173
Group Condition Rv0169 Rv0170 Rv0171 Rv0172 Rv0173
carbon source heptadecanoic 250 uM (C) -1.2 -1.1 -1.5 -1.6 -1.6
carbon source heptadecanoic 250 uM (C) -1.2 -1.5 -1.3 -1.3 -1.3
carbon source Stearic 100 uM (C) -1.3 -0.9 -1.3 -1.5 -1.6
carbon source Stearic 100 uM (C) -1.3 -1.2 -1.2 -1.0 -1.7
stress 7H9 with Bedaquiline 0.15 ug/mL -1.2 -1.4 -1.1 -1.1 -1.3
stress 7H9 with Bedaquiline 0.15 ug/mL -1.3 -1.0 -1.0 -1.2 -1.2
stress 7H9 with Clofazimine 0.072 ug/mL -0.6 -0.7 -0.6 -0.6 -0.6
stress 7H9 with Clofazimine 0.072 ug/mL -0.6 -0.9 -0.4 -0.7 -0.6
stress 7H9 with Ethionamide 0.1 ug/mL -0.8 -1.0 -0.5 -0.2 -0.4
stress 7H9 with Ethionamide 0.1 ug/mL -0.2 -1.0 -0.3 -0.5 -0.5
nitrogen source L-Valine 10 mM (N) -0.4 -0.4 -0.4 -0.6 -0.4
no stress control no stress control -0.5 -0.5 -0.3 -0.3 -0.5
no stress control no stress control -0.4 -0.2 -0.4 -0.4 -0.5
no stress control no stress control -0.3 -0.5 -0.3 -0.5 -0.1
no stress control no stress control -0.1 -0.8 -0.3 +0.3 -0.7
stress 7H9 with Ofloxacin 0.8 ug/mL +0.5 -0.1 +0.4 +1.0 +0.1
stress 7H9 with Rifampicin 0.014 ug/mL +0.3 +0.4 +0.3 +0.4 +0.7
nitrogen source L-Aspartic Acid 10 mM (N) +0.4 +0.3 +0.5 +0.5 +0.5
stress 7H9 with Pretomanid 0.213 ug/mL +0.4 +0.3 +0.6 +0.7 +0.4
carbon source L-Asparagine (C) +0.4 +0.4 +0.6 +0.4 +0.5
stress 7H9 with Clarithromycin 0.967 ug/mL +0.5 +0.4 +0.4 +0.4 +0.6
carbon source L-Asparagine (C) +0.5 +0.6 +0.5 +0.2 +0.6
stress 7H9 with Pretomanid 0.213 ug/mL +0.4 +0.8 +0.5 +0.4 +0.4
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.7 +0.2 +0.5 +0.7 +0.4
nitrogen source L-Asparagine 10 mM (N) +0.6 +0.5 +0.7 +0.6 +0.2
stress 7H9 with Clarithromycin 0.967 ug/mL +0.6 +0.4 +0.6 +0.4 +0.6
stress 7H9 with Levofloxacin 0.3 ug/mL +0.9 +0.1 +0.5 +0.9 +0.2
stress 7H9 with Ofloxacin 0.8 ug/mL +0.7 +0.2 +0.4 +1.0 +0.5
stress 7H9 with Rifampicin 0.014 ug/mL +0.4 +0.4 +0.7 +0.5 +0.9
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.7 +0.3 +0.5 +1.0 +0.5
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Rv0169
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Rv0173
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