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Protein
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Fitness for 5 genes in
Mycobacterium tuberculosis H37Rv
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Rv0036c and Rv0037c are separated by 47 nucleotides
Rv0037c and Rv0038 are separated by 101 nucleotides
Rv0038 and Rv0039c are separated by 91 nucleotides
Rv0039c and Rv0040c are separated by 81 nucleotides
Rv0036c: Rv0036c - Conserved protein, at 39,056 to 39,829
Rv0036c
Rv0037c: Rv0037c - Probable conserved integral membrane protein, at 39,877 to 41,202
Rv0037c
Rv0038: Rv0038 - Conserved protein, at 41,304 to 41,912
Rv0038
Rv0039c: Rv0039c - Possible conserved transmembrane protein, at 42,004 to 42,351
Rv0039c
Rv0040c: Rv0040c - Secreted proline rich protein Mtc28 (proline rich 28 kDa antigen), at 42,433 to 43,365
Rv0040c
Group
Condition
Rv0036c
Rv0037c
Rv0038
Rv0039c
Rv0040c
stress
7H9 with Rifampicin 0.014 ug/mL
+0.3
-1.3
-0.2
-0.0
-1.5
carbon source
L-Asparagine (C)
-0.0
-2.1
+0.1
-0.0
-0.7
stress
7H9 with Rifampicin 0.00045 ug/mL
+0.4
-0.8
-0.3
+0.2
-1.7
pH
pH 4.5
-0.4
-0.9
-0.3
-0.0
-0.6
carbon source
L-Asparagine (C)
-0.0
-1.5
+0.0
+0.1
-0.8
stress
7H9 with Rifampicin 0.00045 ug/mL
+0.2
-0.9
+0.3
+0.5
-2.0
stress
7H9 with Rifampicin 0.014 ug/mL
+0.4
-1.1
+0.3
+0.1
-1.6
carbon source
casaminos 1 mg/mL (C)
+0.3
-1.1
-0.5
+0.3
-0.8
stress
7H9 with Novobiocin 0.004 mM
-0.0
-1.1
+0.4
-0.0
-1.0
stress
7H9 with Clofazimine 0.072 ug/mL
+0.1
-0.7
-0.1
+0.2
-1.2
nitrogen source
Glycine 10 mM (N)
+0.1
-0.8
-0.2
+0.2
-1.1
nitrogen source
L-Aspartic Acid 10 mM (N)
-0.3
-0.4
-0.1
+0.3
-1.2
stress
7H9 with Bedaquiline 0.15 ug/mL
+0.5
-0.5
-0.1
-0.1
-1.3
stress
7H9 with Bedaquiline 0.15 ug/mL
+0.2
-0.5
+0.0
+0.1
-1.4
nitrogen source
Glycine 10 mM (N)
+0.0
-0.6
-0.2
+0.4
-1.0
nitrogen source
L-Asparagine 10 mM (N)
-0.5
-0.8
+0.1
+0.6
-0.9
stress
7H9 with Clofazimine 0.45 ug/mL
+0.2
-0.6
+0.0
+0.2
-1.2
nitrogen source
L-Alanine 10 mM (N)
-0.4
-0.5
-0.2
+0.5
-0.6
stress
7H9 with Clofazimine 0.072 ug/mL
+0.3
-0.7
-0.2
+0.4
-0.9
carbon source
L-Aspartic Acid (C)
+0.3
-0.9
-0.1
+0.3
-0.7
stress
7H9 with Moxifloxacin 0.121 ug/mL
+0.3
+0.0
+0.4
-1.1
-0.7
stress
7H9 with Erythromycin 0.016 mM
-0.4
+0.2
+0.5
-0.2
-0.9
carbon source
D,L-Malic Acid 10 mM (C)
-0.2
-0.8
+0.3
+0.7
-0.8
stress
7H9 with copper (II) chloride 0.08 mM
-0.8
-0.1
+0.2
+0.7
-0.3
stress
7H9 with Sisomicin 0.07 mM
-1.1
-0.3
+1.1
+0.2
+0.1
stress
7H9 with Pyrazinamide 50 ug/mL; pH 5.5
+0.3
+0.5
-0.7
-0.2
+0.7
stress
7H9 with Isoniazid 0.025 ug/mL
-0.3
-0.4
+1.3
-0.7
+0.8
stress
7H9 with Ethionamide 0.1 ug/mL
+0.0
-0.3
+1.1
-0.5
+0.4
stress
7H9 with Ofloxacin 0.8 ug/mL
+0.1
+0.5
+0.8
-0.3
-0.4
stress
7H9 with Isoniazid 0.025 ug/mL
+0.3
-0.6
+1.4
-0.7
+0.5
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