Fitness for 5 genes in Mycobacterium tuberculosis H37Rv

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500 ntRv0035 and Rv0036c are separated by 108 nucleotidesRv0036c and Rv0037c are separated by 47 nucleotidesRv0037c and Rv0038 are separated by 101 nucleotidesRv0038 and Rv0039c are separated by 91 nucleotides Rv0035: Rv0035 - Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 37,259 to 38,947 Rv0035 Rv0036c: Rv0036c - Conserved protein, at 39,056 to 39,829 Rv0036c Rv0037c: Rv0037c - Probable conserved integral membrane protein, at 39,877 to 41,202 Rv0037c Rv0038: Rv0038 - Conserved protein, at 41,304 to 41,912 Rv0038 Rv0039c: Rv0039c - Possible conserved transmembrane protein, at 42,004 to 42,351 Rv0039c
Group Condition Rv0035 Rv0036c Rv0037c Rv0038 Rv0039c
carbon source L-Asparagine (C) +0.0 -0.1 -2.1 +0.1 -0.0
carbon source L-Aspartic Acid (C) -0.1 -0.0 -0.7 -0.3 -0.4
carbon source L-Asparagine (C) -0.1 -0.0 -1.5 +0.0 +0.1
stress 7H9 with Rifampicin 0.014 ug/mL -0.0 +0.3 -1.3 -0.2 -0.0
stress 7H9 with Meropenem 9.6 ug/mL +0.1 -0.2 -0.6 -0.3 -0.2
carbon source D,L-Malic Acid 10 mM (C) -0.0 +0.1 -0.9 -0.4 +0.0
carbon source casaminos 1 mg/mL (C) -0.0 +0.3 -1.1 -0.5 +0.3
no stress control no stress control -0.1 -0.2 -0.2 +0.3 -0.7
carbon source butyrate 10 mM (C) -0.0 +0.1 -0.4 -0.7 +0.3
carbon source Stearic 100 uM (C) -0.2 +0.3 -0.5 -0.5 +0.2
stress 7H9 with Rifampicin 0.00045 ug/mL -0.1 +0.4 -0.8 -0.3 +0.2
nitrogen source L-Alanine 10 mM (N) +0.0 -0.4 -0.5 -0.2 +0.5
nitrogen source L-Asparagine 10 mM (N) -0.0 -0.5 -0.8 +0.1 +0.6
carbon source L-Aspartic Acid (C) -0.1 +0.3 -0.9 -0.1 +0.3
stress 7H9 with Ethambutol 0.75 ug/mL +0.2 -0.1 -0.6 -0.4 +0.4
nitrogen source Glycine 10 mM (N) +0.1 +0.1 -0.8 -0.2 +0.2
stress 7H9 with Rifampicin 0.014 ug/mL +0.0 +0.4 -1.1 +0.3 +0.1
stress 7H9 with Isoniazid 0.025 ug/mL -0.0 -0.3 -0.4 +1.3 -0.7
stress 7H9 with Ethambutol 0.75 ug/mL -0.1 +0.3 -0.7 -0.1 +0.5
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.2 +0.3 +0.0 +0.4 -1.1
carbon source D,L-Malic Acid 10 mM (C) -0.1 -0.2 -0.8 +0.3 +0.7
stress 7H9 with Clofazimine 0.072 ug/mL +0.0 +0.3 -0.7 -0.2 +0.5
stress 7H9 with Rifampicin 0.00045 ug/mL -0.1 +0.2 -0.9 +0.3 +0.5
stress 7H9 with Bedaquiline 0.15 ug/mL +0.3 +0.5 -0.5 -0.1 -0.1
stress 7H9 with Clarithromycin 0.967 ug/mL +0.2 +0.3 -0.2 -0.5 +0.4
stress 7H9 with Ethionamide 0.1 ug/mL -0.0 +0.2 -0.4 +0.8 -0.4
stress 7H9 with Moxifloxacin 0.121 ug/mL +0.1 +0.1 +0.2 +0.5 -0.6
stress 7H9 with Ethionamide 0.1 ug/mL +0.1 -0.0 -0.3 +1.1 -0.5
stress 7H9 with Isoniazid 0.025 ug/mL +0.2 +0.3 -0.6 +1.4 -0.7
stress 7H9 with Ofloxacin 0.8 ug/mL +0.0 +0.1 +0.5 +0.8 -0.3
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