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Cofit
Protein
Homologs
Fitness for 5 genes in
Cupriavidus basilensis FW507-4G11
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
RR42_RS26890 and RR42_RS26895 are separated by 109 nucleotides
RR42_RS26895 and RR42_RS26900 are separated by 82 nucleotides
RR42_RS26900 and RR42_RS26905 are separated by 50 nucleotides
RR42_RS26905 and RR42_RS26910 are separated by 68 nucleotides
RR42_RS26890: RR42_RS26890 - RpiR family transcriptional regulator, at 1,386,768 to 1,387,673
_RS26890
RR42_RS26895: RR42_RS26895 - 3-methylcrotonyl-CoA carboxylase, at 1,387,783 to 1,389,807
_RS26895
RR42_RS26900: RR42_RS26900 - enoyl-CoA hydratase, at 1,389,890 to 1,390,678
_RS26900
RR42_RS26905: RR42_RS26905 - methylcrotonoyl-CoA carboxylase, at 1,390,729 to 1,392,336
_RS26905
RR42_RS26910: RR42_RS26910 - isovaleryl-CoA dehydrogenase, at 1,392,405 to 1,393,586
_RS26910
Group
Condition
RR42
_RS26890
RR42
_RS26895
RR42
_RS26900
RR42
_RS26905
RR42
_RS26910
carbon source
L-Leucine (C)
-0.0
-6.3
-5.9
-4.7
N.D.
carbon source
L-Leucine (C)
-0.2
-5.8
-5.9
-4.9
N.D.
nitrogen source
L-Valine (N)
-0.0
-4.0
-5.6
-4.1
N.D.
nitrogen source
L-Leucine (N)
+0.1
-4.4
-4.0
-4.3
N.D.
nitrogen source
L-Leucine (N)
+0.0
-5.6
-2.4
-4.4
N.D.
nitrogen source
L-Valine (N)
-0.0
-3.6
-3.9
-4.0
N.D.
nitrogen source
L-Isoleucine (N)
-0.3
-1.5
-3.3
-1.7
N.D.
carbon source
L-Alanine (C)
-0.2
-0.5
-3.1
-2.1
N.D.
carbon source
L-Tryptophan (C)
-0.2
-1.2
-2.1
-2.2
N.D.
carbon source
L-Glutamine (C)
+0.2
-0.7
-4.0
-1.3
N.D.
nitrogen source
L-Glutamine (N)
-0.7
-0.3
-4.7
-0.2
N.D.
carbon source
L-Tryptophan (C)
-0.1
-0.8
-2.3
-2.5
N.D.
carbon source
L-Alanine (C)
-0.1
-0.8
-2.3
-2.1
N.D.
carbon source
Ethanol (C)
+0.2
-0.9
-2.5
-2.0
N.D.
carbon source
L-Phenylalanine (C)
+0.2
-0.8
-2.4
-2.2
N.D.
carbon source
Ethanol (C)
-0.2
-0.5
-2.4
-2.1
N.D.
carbon source
4-Hydroxybenzoic Acid (C)
-0.3
-0.6
-2.3
-1.9
N.D.
carbon source
Pimelic (C)
+0.1
-0.5
-2.8
-1.9
N.D.
carbon source
a-Ketoglutaric (C)
+0.2
-0.7
-2.5
-2.0
N.D.
carbon source
L-Proline (C)
+0.3
-0.5
-2.8
-1.9
N.D.
carbon source
Disodium Glutarate (C)
-0.3
-0.5
-1.7
-2.3
N.D.
carbon source
Disodium Glutarate (C)
-0.3
-0.9
-1.1
-2.3
N.D.
carbon source
D-Fructose (C)
-0.4
-0.4
-2.3
-1.4
N.D.
nitrogen source
L-Isoleucine (N)
+0.2
-1.3
-1.6
-1.7
N.D.
oxygen_nitrate
exometabolites; 10% oxygen; 5 mM nitrate
+0.2
-0.9
-2.3
-1.3
N.D.
stress
R2A with D-Cycloserine 0.5 mg/ml
-0.1
-0.4
-2.8
-1.0
N.D.
carbon source
4-Hydroxybenzoic Acid (C)
+0.2
-0.9
-2.0
-1.7
N.D.
carbon source
Carbon source 2-Deoxyadenosine 5-monophosphate 5 mM
-0.9
+2.4
+1.0
+1.8
N.D.
carbon source
Carbon source 2-Deoxyadenosine 5-monophosphate 5 mM
-0.8
+2.0
+1.7
+1.7
N.D.
carbon source
Carbon source 2-Deoxy-D-Ribose 20 mM
-0.4
+1.7
+1.7
+1.8
N.D.
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