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Cofit
Protein
Homologs
Fitness for 5 genes in
Cupriavidus basilensis FW507-4G11
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
RR42_RS25305 and RR42_RS25310 are separated by 544 nucleotides
RR42_RS25310 and RR42_RS25315 are separated by 153 nucleotides
RR42_RS25315 and RR42_RS25320 are separated by 75 nucleotides
RR42_RS25320 and RR42_RS25325 are separated by 42 nucleotides
RR42_RS25305: RR42_RS25305 - transposase, at 1,016,664 to 1,016,822
_RS25305
RR42_RS25310: RR42_RS25310 - LysR family transcriptional regulator, at 1,017,367 to 1,018,290
_RS25310
RR42_RS25315: RR42_RS25315 - methylmalonate-semialdehyde dehydrogenase, at 1,018,444 to 1,019,949
_RS25315
RR42_RS25320: RR42_RS25320 - alcohol dehydrogenase, at 1,020,025 to 1,021,008
_RS25320
RR42_RS25325: RR42_RS25325 - 3-hydroxyisobutyrate dehydrogenase, at 1,021,051 to 1,021,932
_RS25325
Group
Condition
RR42
_RS25305
RR42
_RS25310
RR42
_RS25315
RR42
_RS25320
RR42
_RS25325
carbon source
L-Leucine (C)
-0.3
-0.1
-0.1
-0.5
-0.1
stress
R2A with Polymyxin B sulfate 0.005 mg/ml
-0.4
-0.2
+0.0
-0.4
-0.0
carbon source
4-Hydroxybenzoic Acid (C)
-0.6
-0.0
-0.1
-0.2
-0.1
carbon source
Protocatechuic Acid (C)
-0.1
-0.0
+0.1
-0.3
-0.5
lb
LB
-1.0
+0.5
+0.1
+0.1
-0.4
oxygen_nitrate
exometabolites; 5% oxygen; 5 mM nitrate
-0.7
+0.1
+0.1
+0.0
-0.1
stress
R2A with Chloride 300 mM
-0.6
-0.0
+0.1
-0.1
+0.1
carbon source
D-Gluconic Acid (C)
+0.2
-0.2
-0.1
-0.1
-0.4
carbon source
4-Hydroxybenzoic Acid (C)
+0.3
-0.2
-0.1
-0.3
-0.2
carbon source
Suberic (C)
-0.3
+0.0
+0.2
+0.1
-0.4
stress
R2A with Lomefloxacin 0.00075 mM
+0.3
-0.2
-0.2
-0.2
+0.1
carbon source
pyruvate (C)
+0.5
-0.1
-0.3
-0.2
-0.2
carbon source
Carbon source 2-Deoxy-D-Ribose 20 mM
-0.5
-0.1
-0.0
+0.2
+0.2
stress
R2A with copper (II) chloride 0.25 mM
+0.4
-0.1
-0.4
+0.2
-0.2
stress
R2A with Zinc 0.1 mM
+0.5
-0.1
-0.2
-0.3
+0.1
carbon source
adipate (C)
+0.2
+0.1
+0.1
-0.4
+0.2
carbon source
Trisodium citrate (C)
+0.6
+0.0
-0.1
-0.2
-0.0
nitrogen source
Glucuronamide (N)
+0.6
-0.3
+0.0
-0.0
-0.0
stress
R2A with Doxycycline hyclate 0.0001 mg/ml
+0.6
-0.1
-0.2
-0.1
+0.1
carbon source
D,L-Lactate (C)
+0.6
-0.1
-0.2
-0.2
+0.1
r2a
R2A
+0.4
-0.2
-0.2
+0.1
+0.1
carbon source
Carbon source 2-Deoxy-D-Ribose 20 mM
-0.4
+0.2
+0.2
+0.3
+0.2
carbon source
Carbon source 2-Deoxyadenosine 5-monophosphate 5 mM
-0.7
+0.0
+0.3
+0.6
+0.3
carbon source
Octanoic (C)
+0.1
-0.2
+0.3
-0.2
+0.5
stress
R2A with Vancomycin 0.5 mg/ml
+0.8
-0.2
-0.4
+0.3
+0.1
stress
R2A with Nickel (II) chloride 0.35 mM
+0.1
+0.3
-0.1
+0.3
+0.1
nitrogen source
L-Glutamine (N)
+0.3
+0.2
+0.1
+0.1
+0.3
oxygen_nitrate
exometabolites; 10% oxygen; 5 mM nitrate
+0.3
+0.3
-0.1
+0.6
-0.1
nitrogen source
D-Alanine (N)
+0.3
+0.2
+0.2
+0.0
+0.3
stress
R2A with Cisplatin 0.001 mg/ml
+1.0
-0.1
-0.2
+0.0
+0.6
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