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Cofit
Protein
Homologs
Fitness for 5 genes in
Cupriavidus basilensis FW507-4G11
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
RR42_RS25270 and RR42_RS25275 are separated by 241 nucleotides
RR42_RS25275 and RR42_RS25280 are separated by 180 nucleotides
RR42_RS25280 and RR42_RS25285 overlap by 4 nucleotides
RR42_RS25285 and RR42_RS25290 are separated by 41 nucleotides
RR42_RS25270: RR42_RS25270 - MFS transporter, at 1,009,010 to 1,010,350
_RS25270
RR42_RS25275: RR42_RS25275 - LysR family transcriptional regulator, at 1,010,592 to 1,011,500
_RS25275
RR42_RS25280: RR42_RS25280 - 3-hydroxy-3-methylglutaryl-CoA lyase, at 1,011,681 to 1,012,652
_RS25280
RR42_RS25285: RR42_RS25285 - CoA-transferase, at 1,012,649 to 1,013,800
_RS25285
RR42_RS25290: RR42_RS25290 - ABC transporter substrate-binding protein, at 1,013,842 to 1,014,852
_RS25290
Group
Condition
RR42
_RS25270
RR42
_RS25275
RR42
_RS25280
RR42
_RS25285
RR42
_RS25290
stress
R2A with D-Cycloserine 0.5 mg/ml
-0.4
+0.2
-0.7
-0.3
-0.1
oxygen_nitrate
exometabolites; 10% oxygen; 5 mM nitrate
-0.2
+0.0
-0.6
+0.1
-0.5
carbon source
L-Leucine (C)
-0.0
-0.1
-0.4
-0.4
-0.2
carbon source
butyrate (C)
-0.3
-0.0
-0.3
-0.2
-0.1
oxygen_nitrate
exometabolites; 5% oxygen; 5 mM nitrate
-0.2
+0.0
-0.3
+0.0
-0.5
stress
R2A with Polymyxin B sulfate 0.005 mg/ml
-0.2
-0.3
-0.2
-0.2
+0.0
nitrogen source
L-Glutamine (N)
-0.0
+0.2
-0.7
-0.1
-0.3
stress
R2A with nitrate 200 mM
+0.1
-0.0
-0.4
-0.2
-0.5
stress
R2A with Chlorite 4 mM
-0.3
+0.2
-0.5
+0.1
-0.3
carbon source
adipate (C)
-0.4
-0.0
+0.1
+0.1
-0.5
stress
R2A with Cisplatin 0.001 mg/ml
-0.2
+0.1
-0.7
+0.2
-0.1
stress
R2A with Paraquat dichloride 0.064 mg/ml
+0.2
-0.1
-0.7
+0.1
-0.3
lb
LB
-0.4
+0.3
+0.2
-0.9
+0.1
carbon source
Carbon source 2-Deoxyadenosine 5-monophosphate 5 mM
+0.1
+0.1
-0.4
+0.1
-0.4
carbon source
L-Threonine (C)
+0.3
-0.0
-0.7
-0.0
-0.1
carbon source
L-Malic (C)
-0.1
-0.2
+0.4
-0.0
-0.3
carbon source
Valeric (C)
-0.1
+0.2
+0.2
-0.1
-0.4
carbon source
Valeric (C)
+0.3
-0.1
+0.2
-0.3
-0.2
nitrogen source
Glucuronamide (N)
+0.0
-0.0
+0.6
-0.3
-0.3
stress
R2A with sodium fluoride 100 mM
-0.2
+0.0
+0.0
-0.3
+0.4
carbon source
Carbon source D,L-Lactate 10 mM
-0.2
-0.0
+0.3
+0.2
-0.3
stress
R2A with Dimethyl Sulfoxide 5 vol%
+0.1
-0.1
-0.3
+0.2
+0.2
stress
R2A with copper (II) chloride 0.25 mM
+0.3
+0.2
-0.5
+0.1
+0.0
carbon source
Protocatechuic Acid (C)
-0.1
-0.1
+0.4
-0.2
+0.2
stress
R2A with Lomefloxacin 0.001 mM
+0.2
-0.0
-1.0
+0.4
+0.6
carbon source
adipate (C)
-0.2
-0.0
+0.6
-0.2
+0.1
carbon source
Carbon source Phenylacetic 2.5 mM
+0.1
+0.0
+0.6
-0.2
-0.2
carbon source
4-Hydroxybenzoic Acid (C)
-0.1
-0.2
+0.6
-0.1
+0.2
carbon source
L-Asparagine (C)
+0.3
+0.4
-0.3
+0.3
+0.0
carbon source
Suberic (C)
+0.3
-0.0
+0.8
-0.1
-0.2
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