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Cofit
Protein
Homologs
Fitness for 5 genes in
Cupriavidus basilensis FW507-4G11
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
RR42_RS12065 and RR42_RS12070 are separated by 47 nucleotides
RR42_RS12070 and RR42_RS12075 overlap by 4 nucleotides
RR42_RS12075 and RR42_RS12080 are separated by 81 nucleotides
RR42_RS12080 and RR42_RS12085 are separated by 152 nucleotides
RR42_RS12065: RR42_RS12065 - acyl-CoA-binding protein, at 2,586,250 to 2,586,519
_RS12065
RR42_RS12070: RR42_RS12070 - MFS transporter, at 2,586,567 to 2,588,036
_RS12070
RR42_RS12075: RR42_RS12075 - hypothetical protein, at 2,588,033 to 2,588,503
_RS12075
RR42_RS12080: RR42_RS12080 - lipase, at 2,588,585 to 2,589,301
_RS12080
RR42_RS12085: RR42_RS12085 - glyoxalase, at 2,589,454 to 2,589,897
_RS12085
Group
Condition
RR42
_RS12065
RR42
_RS12070
RR42
_RS12075
RR42
_RS12080
RR42
_RS12085
carbon source
Protocatechuic Acid (C)
-1.0
-0.7
N.D.
-0.3
-0.3
carbon source
Carbon source 2-Deoxyadenosine 5-monophosphate 5 mM
-0.5
-0.3
N.D.
+0.1
-1.3
stress
R2A with Cisplatin 0.001 mg/ml
-0.3
-0.2
N.D.
-0.0
-1.4
stress
R2A with Polymyxin B sulfate 0.005 mg/ml
-0.3
-0.2
N.D.
-0.6
-0.6
stress
R2A with Nickel (II) chloride 0.35 mM
-1.2
-0.2
N.D.
+0.2
-0.2
carbon source
propionate (C)
-0.5
+0.0
N.D.
+0.3
-0.8
stress
R2A with Vancomycin 0.5 mg/ml
-0.8
-0.1
N.D.
-0.5
+0.3
carbon source
Valeric (C)
-0.7
+0.2
N.D.
-0.4
+0.3
carbon source
Dodecandioic (C)
-0.6
-0.3
N.D.
-0.1
+0.7
carbon source
Suberic (C)
-1.0
+0.0
N.D.
-0.0
+0.6
carbon source
D-Gluconic Acid (C)
-0.7
+0.1
N.D.
-0.2
+0.6
oxygen_nitrate
exometabolites; 10% oxygen; 5 mM nitrate
-0.6
-0.0
N.D.
-0.5
+0.8
carbon source
Valeric (C)
-0.6
-0.1
N.D.
-0.3
+0.8
carbon source
Azelaic (C)
-0.8
-0.3
N.D.
+0.0
+1.0
carbon source
D,L-Lactate (C)
-0.5
-0.2
N.D.
-0.3
+0.8
oxygen_nitrate
exometabolites; 10% oxygen; 5 mM nitrate
+0.3
-0.4
N.D.
-0.4
+0.5
carbon source
L-Phenylalanine (C)
+0.7
-0.2
N.D.
-0.5
+0.4
stress
R2A with Lomefloxacin 0.00075 mM
-0.6
-0.1
N.D.
+0.1
+1.0
stress
R2A with Paraquat dichloride 0.064 mg/ml
-0.7
-0.3
N.D.
+0.4
+1.0
carbon source
butyrate (C)
+0.4
-0.4
N.D.
-0.2
+0.7
lb
LB
+1.2
+0.4
N.D.
-0.8
-0.2
carbon source
Disodium Glutarate (C)
-0.3
+0.0
N.D.
-0.1
+1.1
stress
R2A with A22 0.01 mg/ml
-0.4
+0.2
N.D.
+0.3
+0.6
carbon source
Azelaic (C)
+0.1
-0.7
N.D.
-0.4
+1.8
nitrogen source
L-Valine (N)
-0.4
+0.2
N.D.
+0.7
+0.4
stress
R2A with Lomefloxacin 0.001 mM
+0.1
-0.4
N.D.
-0.3
+1.6
nitrogen source
L-Leucine (N)
-0.5
+0.1
N.D.
+0.8
+0.6
carbon source
a-Ketoglutaric (C)
+0.3
+0.3
N.D.
-0.1
+0.8
carbon source
Protocatechuic Acid (C)
-0.6
-0.1
N.D.
+0.3
+1.7
nitrogen source
L-Isoleucine (N)
-0.4
+0.2
N.D.
+0.3
+1.4
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