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Cofit
Protein
Homologs
Fitness for 5 genes in
Pseudomonas fluorescens FW300-N2E2
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Pf6N2E2_5233 and Pf6N2E2_5234 are separated by 119 nucleotides
Pf6N2E2_5234 and Pf6N2E2_5235 are separated by 2 nucleotides
Pf6N2E2_5235 and Pf6N2E2_5236 are separated by 62 nucleotides
Pf6N2E2_5236 and Pf6N2E2_5237 overlap by 21 nucleotides
Pf6N2E2_5233 - Ferrochelatase, protoheme ferro-lyase (EC 4.99.1.1), at 6,030,944 to 6,031,969
_5233
Pf6N2E2_5234 - Uracil permease, at 6,032,089 to 6,033,363
_5234
Pf6N2E2_5235 - Uracil phosphoribosyltransferase (EC 2.4.2.9), at 6,033,366 to 6,034,004
_5235
Pf6N2E2_5236 - hypothetical protein, at 6,034,067 to 6,034,189
_5236
Pf6N2E2_5237 - Hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8), at 6,034,169 to 6,034,726
_5237
Group
Condition
Pf6N2E2
_5233
Pf6N2E2
_5234
Pf6N2E2
_5235
Pf6N2E2
_5236
Pf6N2E2
_5237
stress
Nickel (II) chloride 0.0025 M
N.D.
-0.3
-0.4
-0.7
-4.7
stress
thiosulfate 0.25 M
N.D.
-0.2
-0.1
-2.2
-1.9
stress
Nickel (II) chloride 0.0025 M
N.D.
+0.4
-0.3
+0.1
-4.3
stress
Bile salts 0.0125 M
N.D.
+0.2
-0.4
+0.5
-2.5
nitrogen source
nitrogen source nitrite 1mM
N.D.
+0.1
+0.1
-0.6
-1.6
stress
RCH2 defined with copper (II) chloride 0.03 mM
N.D.
-0.0
+0.4
-1.8
-0.4
nitrogen source
nitrogen source nitrate 20mM
N.D.
+0.6
+0.1
-1.3
-0.9
stress
Hydroxylamine 0.5 M
N.D.
+0.1
+0.5
-0.4
-1.7
motility
inner cut, LB soft agar motility assay
N.D.
+0.0
+0.7
-1.0
-1.1
carbon source
Ying_sugar7 rep B; time point 2
N.D.
-0.0
-0.1
+0.6
-1.7
carbon source
Ying_Nucleobase14 rep B; time point 2
N.D.
-0.7
-0.9
+0.5
+0.3
stress
phosphite 0.25 M
N.D.
-0.2
-0.2
+0.8
-1.3
carbon source
RCH2_defined
N.D.
+0.5
+0.2
-1.5
+0.3
nitrogen source
nitrogen source nitrite 5mM
N.D.
+0.5
+0.4
-1.3
+0.3
carbon source
Ying_Nucleobase14 rep C; time point 3
N.D.
-0.3
-1.1
+0.9
+0.8
stress
Fusidic 0.4 mg/ml
N.D.
-0.3
-0.6
+0.7
+0.8
stress
Cobalt chloride 0.6 mM
N.D.
-0.3
-0.7
+0.4
+1.2
stress
Phosphomycin 0.004 mg/ml
N.D.
-0.6
-1.6
+0.7
+2.1
stress
Cobalt chloride 0.4 mM
N.D.
-0.2
-0.7
+0.6
+1.0
stress
Fusidic 0.3 mg/ml
N.D.
-0.0
-0.7
+0.9
+0.9
carbon source
Ying_OrganicAcid7 rep C; time point 3
N.D.
-0.1
-0.6
+0.4
+1.4
carbon source
Ying_Nucleobase14 rep A; time point 3
N.D.
+0.2
-1.2
+1.0
+1.2
stress
Cobalt chloride 0.6 mM
N.D.
-0.7
-1.1
+1.1
+1.7
stress
tungstate 0.05 M
N.D.
+0.1
-0.7
+1.0
+0.8
carbon source
Ying_Nucleobase14 rep B; time point 3
N.D.
+0.3
-1.4
+0.6
+1.7
stress
Cobalt chloride 0.6 mM
N.D.
-0.7
-0.8
+1.7
+1.2
carbon source
Ying_OrganicAcid7 rep B; time point 3
N.D.
-0.4
-0.1
+0.5
+1.4
stress
Cobalt chloride 0.6 mM
N.D.
-0.6
-1.1
+1.4
+2.0
nitrogen source
L-Serine (N)
N.D.
-0.4
+0.7
+0.1
+1.7
nitrogen source
L-Serine (N)
N.D.
+0.1
+0.7
-0.1
+1.9
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Pf6N2E2_5235
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