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Fitness for 5 genes in
Methanococcus maripaludis S2
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500 nt
MMP_RS02905 and MMP_RS02910 are separated by 170 nucleotides
MMP_RS02910 and MMP_RS02915 are separated by 34 nucleotides
MMP_RS02915 and MMP_RS02920 are separated by 77 nucleotides
MMP_RS02920 and MMP_RS02925 are separated by 21 nucleotides
MMP_RS02905: MMP_RS02905 - 2-thiouracil desulfurase family protein, at 553,444 to 553,992
_RS02905
MMP_RS02910: MMP_RS02910 - ABC transporter substrate-binding protein, at 554,163 to 554,957
_RS02910
MMP_RS02915: MMP_RS02915 - amino acid ABC transporter permease, at 554,992 to 555,651
_RS02915
MMP_RS02920: MMP_RS02920 - DMT family transporter, at 555,729 to 556,619
_RS02920
MMP_RS02925: MMP_RS02925 - ornithine carbamoyltransferase, at 556,641 to 557,555
_RS02925
Group
Condition
MMP
_RS02905
MMP
_RS02910
MMP
_RS02915
MMP
_RS02920
MMP
_RS02925
stress
McCas_H2_complete 5-Fluorouracil 0.00833333333333333 mM
-0.7
-0.4
-0.9
+0.0
N.D.
no stress control
McCas_H2_complete no stress control
-0.9
-0.5
+0.1
-0.2
N.D.
nutrient t2
H2 deepwell autotrophic conditions
-0.9
-0.3
+0.3
-0.3
N.D.
nitrogen source
H2 N-free with 10mM L-Alanine
-1.0
-0.3
-0.2
+0.2
N.D.
mixed community
Mixed culture; Syntrophotalea carbinolica 1:1 starting OD to methanogen; Ethanolamine_timecourse2; 20 generations
+0.2
-0.1
-1.3
+0.1
N.D.
stress
McCas_H2_complete Benzethonium chloride 0.00625 mM
+0.3
-0.6
-0.9
+0.1
N.D.
stress
McCas_H2_complete Anhydrotetracycline 0.05 mM
-0.5
-0.4
-0.4
+0.3
N.D.
stress
McCas_H2_complete sulfate 125 mM
+0.2
-0.6
-0.6
+0.2
N.D.
stress
McCas_H2_complete Thioridazine 0.1 mM
+0.4
-0.8
-0.4
+0.1
N.D.
nitrogen source
H2 N-free with 10mM Uridine
-0.4
-0.5
+0.5
-0.3
N.D.
nutrient t2
H2 deepwell casamino FREE
-0.7
-0.3
+0.6
-0.3
N.D.
nutrient t2
H2 deepwell acetate and casamino FREE
-0.6
-0.3
+0.7
-0.3
N.D.
nutrient t2
H2 deepwell acetate and casamino FREE
-0.8
-0.4
+0.8
-0.0
N.D.
stress
McCas_formate_complete dimetridazole 0.00416666666666667 mM
-0.8
+0.5
+0.0
+0.2
N.D.
stress
McCas_H2_complete Rifampicin 0.5 mM
-0.6
+0.3
+0.6
-0.2
N.D.
stress
McCas_H2_complete Cadmium chloride hemipentahydrate 0.555555555555556 mM
-0.1
-0.6
+0.6
+0.4
N.D.
stress
McCas_H2_complete potassium hexahydroxoantimonate 0.125 mM
-0.7
+0.7
+0.0
+0.2
N.D.
nitrogen source
Formate N-free with 2mM Adenosine
-0.1
+0.4
+0.6
-0.5
N.D.
nutrient t2
H2 deepwell acetate and vitamin FREE
+0.3
-0.6
+0.3
+0.3
N.D.
nitrogen source
H2 N-free with 10mM B-Alanine
+1.1
+0.1
-0.6
-0.0
N.D.
stress
McCas_H2_complete Nitrofurantoin 0.1 mM
-0.5
-0.0
+1.1
-0.0
N.D.
stress
McCas_formate_complete sulfate 125 mM
+0.7
-0.8
+0.4
+0.5
N.D.
stress
McCas_H2_complete dimetridazole 0.00833333333333333 mM
+0.4
-0.4
+1.0
+0.0
N.D.
stress
McCas_formate_complete rubidium chloride 62.5 mM
-0.2
+0.4
+0.5
+0.6
N.D.
stress
McCas_formate_complete Phenazine methosulfate 0.0333333333333333 mM
+0.3
-0.2
+0.6
+0.5
N.D.
stress
McCas_H2_complete Chloride 250 mM
-0.3
+0.5
+1.1
-0.0
N.D.
stress
McCas_H2_complete 2,2-dibromo-2-cyanoacetamide 0.0333333333333333 mM
+0.3
+0.3
+0.8
-0.1
N.D.
nutrient t1
Mc formate, casamino free, with 10mM L-Threonine
+1.0
+0.5
-0.1
+0.1
N.D.
stress
McCas_H2_complete gold (III) chloride 0.0357142857142857 mM
+0.4
+0.2
+1.0
-0.1
N.D.
stress
McCas_formate_complete 3-nitroxypropanol 0.00833333333333333 mM
+0.1
+0.4
+0.8
+0.3
N.D.
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