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Cofit
Protein
Homologs
Fitness for 5 genes in
Acidovorax sp. GW101-3H11
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500 nt
Ac3H11_905 and Ac3H11_906 overlap by 4 nucleotides
Ac3H11_906 and Ac3H11_907 are separated by 154 nucleotides
Ac3H11_907 and Ac3H11_908 are separated by 136 nucleotides
Ac3H11_908 and Ac3H11_909 are separated by 56 nucleotides
Ac3H11_905 - Rhodanese domain protein UPF0176, cyanobacterial/alphaproteobacterial subgroup, at 19,736 to 20,737
_905
Ac3H11_906 - Glutathione S-transferase domain protein, at 20,734 to 21,429
_906
Ac3H11_907 - hypothetical protein, at 21,584 to 21,802
_907
Ac3H11_908 - Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation, at 21,939 to 22,475
_908
Ac3H11_909 - Sulfate and thiosulfate import ATP-binding protein CysA (EC 3.6.3.25), at 22,532 to 23,656
_909
Group
Condition
Ac3H11
_905
Ac3H11
_906
Ac3H11
_907
Ac3H11
_908
Ac3H11
_909
stress
copper (II) chloride 2 mM
+0.2
-0.3
-2.4
N.D.
-0.9
nitrogen source
Ammonium chloride (N)
+0.1
+0.1
-3.1
N.D.
-0.4
stress
Cisplatin 0.005 mg/ml
+0.2
-0.1
-3.4
N.D.
+0.2
nitrogen source
L-Isoleucine (N)
+0.0
-0.4
-2.6
N.D.
+0.2
pH
LB, pH10
+0.1
+0.4
-3.2
N.D.
-0.1
phage
phage 93.1
+0.2
-0.2
-2.8
N.D.
+0.2
carbon source
L-Asparagine (C)
+0.0
-0.1
-1.4
N.D.
-0.5
stress
Cisplatin 0.0025 mg/ml
+0.0
-0.0
-2.5
N.D.
+0.6
stress
Chlorite 0.1 mM
+0.3
-0.0
-1.9
N.D.
-0.2
nitrogen source
L-Leucine (N)
+0.3
+0.0
-1.5
N.D.
-0.2
stress
perchlorate 10 mM
+0.2
-0.0
-1.1
N.D.
-0.4
carbon source
D-Lactate (C)
+0.2
-0.1
-1.2
N.D.
-0.2
stress
Dimethyl Sulfoxide 6 vol%
+0.2
+0.2
-2.0
N.D.
+0.3
stress
Phosphomycin 0.06 mg/ml
+0.2
-0.0
-1.3
N.D.
+0.2
carbon source
succinate (C)
+0.2
+0.3
-1.3
N.D.
-0.1
carbon source
L-Lactate (C)
+0.1
+0.2
-0.8
N.D.
-0.4
stress
Bacitracin 0.032 mg/ml
+0.2
+0.2
-1.1
N.D.
+0.1
lb
LB
+0.2
+0.2
-1.1
N.D.
+0.1
stress
nitrite 10 mM
+0.0
-0.3
-0.7
N.D.
+0.7
nitrogen source
L-Glutamine (N)
-0.0
-0.0
+0.5
N.D.
-0.9
motility
inner cut, R2A soft agar motility assay
+0.4
-0.0
+0.4
N.D.
-0.7
stress
Sisomicin 0.001 mg/ml
+0.1
+0.3
-0.9
N.D.
+0.6
stress
Cobalt chloride 0.32 mM
-0.6
-0.1
+1.3
N.D.
-0.4
carbon source
D-Lactate (C)
+0.0
+0.2
+1.0
N.D.
-0.2
stress
Cobalt chloride 0.4 mM
-0.4
+0.1
+1.1
N.D.
+0.6
stress
Paraquat dichloride 0.01 mg/ml
+0.2
-0.4
+1.1
N.D.
+0.5
nitrogen source
L-Alanine (N)
+0.1
-0.0
+1.0
N.D.
+0.4
carbon source
pyruvate (C)
+0.0
+0.1
+0.9
N.D.
+0.5
carbon source
L-Lactate (C)
+0.2
+0.3
+1.3
N.D.
-0.0
lb
LB
+0.1
+0.2
+1.1
N.D.
+0.6
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