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Cofit
Protein
Homologs
Fitness for 5 genes in
Acidovorax sp. GW101-3H11
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500 nt
Ac3H11_4583 and Ac3H11_4584 are separated by 591 nucleotides
Ac3H11_4584 and Ac3H11_4585 are separated by 264 nucleotides
Ac3H11_4585 and Ac3H11_4586 overlap by 4 nucleotides
Ac3H11_4586 and Ac3H11_4587 are separated by 343 nucleotides
Ac3H11_4583 - Heavy metal RND efflux outer membrane protein, CzcC family, at 183,857 to 185,212
_4583
Ac3H11_4584 - hypothetical protein, at 185,804 to 186,034
_4584
Ac3H11_4585 - DNA-binding heavy metal response regulator, at 186,299 to 186,985
_4585
Ac3H11_4586 - Heavy metal sensor histidine kinase, at 186,982 to 188,319
_4586
Ac3H11_4587 - Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4), at 188,663 to 190,936
_4587
Group
Condition
Ac3H11
_4583
Ac3H11
_4584
Ac3H11
_4585
Ac3H11
_4586
Ac3H11
_4587
stress
Zinc 1 mM
-1.5
N.D.
-0.4
-1.1
-3.7
nitrogen source
L-Isoleucine (N)
-0.5
N.D.
-0.6
-0.1
-0.2
pH
LB, pH10
-0.7
N.D.
-0.4
-0.1
-0.1
nitrogen source
L-Alanine (N)
-0.2
N.D.
-0.5
-0.2
-0.3
stress
copper (II) chloride 2 mM
-0.8
N.D.
+0.0
-0.1
-0.4
nitrogen source
D-Alanine (N)
-0.3
N.D.
-0.4
-0.1
-0.4
stress
nitrite 10 mM
-0.2
N.D.
+0.0
-0.1
-0.4
nitrogen source
L-Arginine (N)
-0.2
N.D.
-0.3
-0.2
+0.0
stress
copper (II) chloride 1 mM
-0.4
N.D.
+0.1
-0.1
-0.2
stress
Bacitracin 0.032 mg/ml
-0.7
N.D.
+0.2
+0.0
+0.0
motility
inner cut, R2A soft agar motility assay
+0.1
N.D.
-0.5
+0.3
-0.2
stress
Nickel (II) chloride 0.8 mM
-0.5
N.D.
-0.0
-0.0
+0.2
motility
inner cut, R2A soft agar motility assay
+0.0
N.D.
-0.3
-0.2
+0.4
stress
copper (II) chloride 1 mM
-0.3
N.D.
+0.4
-0.1
-0.0
stress
D-Cycloserine 0.05 mg/ml
-0.3
N.D.
+0.5
-0.1
-0.1
stress
Polymyxin B sulfate 0.0001 mg/ml
+0.0
N.D.
-0.4
+0.2
+0.2
lb
LB
-0.3
N.D.
+0.4
-0.1
+0.0
stress
Cobalt chloride 0.16 mM
+0.2
N.D.
-0.3
+0.1
+0.2
stress
Cisplatin 0.0025 mg/ml
-0.3
N.D.
+0.2
+0.2
+0.1
stress
Bacitracin 0.008 mg/ml
-0.2
N.D.
+0.2
+0.2
-0.1
stress
Chlorite 0.1 mM
-0.0
N.D.
+0.5
-0.1
-0.1
carbon source
D-Gluconic Acid (C)
-0.2
N.D.
+0.1
+0.2
+0.2
stress
Cobalt chloride 0.32 mM
+0.2
N.D.
-0.2
+0.1
+0.2
carbon source
pyruvate (C)
+0.1
N.D.
+0.3
+0.2
-0.1
stress
nitrate 100 mM
+0.2
N.D.
+0.2
+0.2
+0.1
stress
perchlorate 10 mM
+0.1
N.D.
+0.2
+0.3
+0.1
carbon source
succinate (C)
+0.3
N.D.
+0.5
+0.0
-0.1
carbon source
D-Lactate (C)
+0.2
N.D.
+0.3
+0.2
+0.4
stress
Cobalt chloride 0.4 mM
+0.4
N.D.
+0.1
-0.2
+1.6
stress
Cobalt chloride 0.32 mM
+0.9
N.D.
+0.0
-0.1
+1.0
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