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Cofit
Protein
Homologs
Fitness for 5 genes in
Acidovorax sp. GW101-3H11
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Ac3H11_4485 and Ac3H11_4486 are separated by 112 nucleotides
Ac3H11_4486 and Ac3H11_4487 are separated by 15 nucleotides
Ac3H11_4487 and Ac3H11_4488 are separated by 72 nucleotides
Ac3H11_4488 and Ac3H11_4489 are separated by 85 nucleotides
Ac3H11_4485 - Formyltetrahydrofolate deformylase (EC 3.5.1.10), at 71,625 to 72,476
_4485
Ac3H11_4486 - diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s), at 72,589 to 74,889
_4486
Ac3H11_4487 - Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1), at 74,905 to 75,825
_4487
Ac3H11_4488 - Nitrate/nitrite sensor protein (EC 2.7.3.-), at 75,898 to 77,877
_4488
Ac3H11_4489 - Nitrate/nitrite response regulator protein, at 77,963 to 78,664
_4489
Group
Condition
Ac3H11
_4485
Ac3H11
_4486
Ac3H11
_4487
Ac3H11
_4488
Ac3H11
_4489
carbon source
succinate (C)
N.D.
+0.1
-1.2
-0.0
N.D.
stress
Ceftazidime 0.01 mg/ml
N.D.
-0.1
-0.7
-0.3
N.D.
carbon source
succinate (C)
N.D.
-0.1
-0.8
-0.1
N.D.
pH
LB, pH10
N.D.
-0.2
-0.6
-0.1
N.D.
stress
Polymyxin B sulfate 0.0001 mg/ml
N.D.
-0.3
-0.6
-0.0
N.D.
carbon source
D-Fructose (C)
N.D.
+0.1
-0.9
-0.0
N.D.
temperature
LB 30C
N.D.
+0.0
-0.7
-0.1
N.D.
carbon source
pyruvate (C)
N.D.
+0.1
-0.7
-0.1
N.D.
temperature
LB 23C
N.D.
-0.2
-0.5
-0.1
N.D.
carbon source
D-Lactate (C)
N.D.
-0.1
-0.4
-0.2
N.D.
phage
phage 93.1
N.D.
-0.3
-0.5
+0.2
N.D.
stress
Phosphomycin 0.06 mg/ml
N.D.
-0.2
-0.4
+0.1
N.D.
carbon source
L-Lactate (C)
N.D.
+0.2
-0.7
+0.0
N.D.
nitrogen source
Ammonium chloride (N)
N.D.
+0.3
-0.1
-0.5
N.D.
stress
Cisplatin 0.005 mg/ml
N.D.
-0.5
+0.7
-0.4
N.D.
stress
Chlorite 0.1 mM
N.D.
-0.2
-0.2
+0.3
N.D.
carbon source
a-Ketoglutaric (C)
N.D.
+0.3
-0.2
-0.2
N.D.
stress
Cisplatin 0.0025 mg/ml
N.D.
-0.1
+0.6
-0.3
N.D.
phage
phage 93.1
N.D.
-0.2
+0.9
-0.1
N.D.
pH
LB, pH10
N.D.
+0.1
+0.9
-0.4
N.D.
nitrogen source
L-Isoleucine (N)
N.D.
+0.1
+0.6
-0.0
N.D.
lb
LB
N.D.
-0.0
+0.8
-0.1
N.D.
lb
LB
N.D.
+0.2
+0.4
+0.2
N.D.
stress
copper (II) chloride 2 mM
N.D.
+0.0
+1.0
-0.3
N.D.
carbon source
succinate (C)
N.D.
-0.2
+1.2
-0.1
N.D.
stress
Zinc 1 mM
N.D.
+0.0
+0.6
+0.3
N.D.
motility
inner cut, R2A soft agar motility assay
N.D.
+0.2
+0.6
+0.0
N.D.
stress
Chlorate 20 mM
N.D.
-0.2
-1.2
+2.2
N.D.
nitrogen source
D-Alanine (N)
N.D.
+0.3
+0.4
+0.2
N.D.
stress
Paraquat dichloride 0.01 mg/ml
N.D.
-0.1
+0.9
+0.3
N.D.
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