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Cofit
Protein
Homologs
Fitness for 5 genes in
Acidovorax sp. GW101-3H11
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Ac3H11_4166 and Ac3H11_4167 are separated by 24 nucleotides
Ac3H11_4167 and Ac3H11_4168 are separated by 49 nucleotides
Ac3H11_4168 and Ac3H11_4169 are separated by 75 nucleotides
Ac3H11_4169 and Ac3H11_4170 are separated by 34 nucleotides
Ac3H11_4166 - Alanyl-tRNA synthetase (EC 6.1.1.7), at 420,760 to 423,390
_4166
Ac3H11_4167 - hypothetical protein, at 423,415 to 423,639
_4167
Ac3H11_4168 - 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22), at 423,689 to 424,606
_4168
Ac3H11_4169 - Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1), at 424,682 to 425,833
_4169
Ac3H11_4170 - 4-hydroxyproline epimerase (EC 5.1.1.8), at 425,868 to 426,812
_4170
Group
Condition
Ac3H11
_4166
Ac3H11
_4167
Ac3H11
_4168
Ac3H11
_4169
Ac3H11
_4170
stress
Bacitracin 0.032 mg/ml
N.D.
-0.4
-0.2
-0.2
-0.4
stress
Cobalt chloride 0.4 mM
N.D.
-0.6
+0.1
-0.4
-0.1
stress
Paraquat dichloride 0.01 mg/ml
N.D.
-0.5
+0.1
-0.3
-0.2
stress
copper (II) chloride 1 mM
N.D.
-1.1
+0.1
+0.1
+0.0
carbon source
propionate (C)
N.D.
-1.0
-0.0
+0.0
+0.1
stress
D-Cycloserine 0.05 mg/ml
N.D.
-0.6
-0.4
+0.2
+0.0
lb
LB
N.D.
-0.8
+0.1
+0.1
-0.1
stress
copper (II) chloride 2 mM
N.D.
-1.2
+0.4
+0.3
+0.1
carbon source
L-Lactate (C)
N.D.
-0.7
+0.1
+0.0
+0.3
stress
perchlorate 10 mM
N.D.
-0.8
-0.0
+0.3
+0.5
carbon source
L-Arabinose (C)
N.D.
-0.7
+0.1
+0.2
+0.4
nitrogen source
L-Leucine (N)
N.D.
-0.3
+0.2
+0.3
+0.3
carbon source
L-Arabinose (C)
N.D.
-0.2
+0.2
+0.4
+0.3
stress
Chloramphenicol 0.0005 mg/ml
N.D.
+0.5
+0.1
-0.2
+0.4
phage
phage 93.1
N.D.
+0.7
+0.2
-0.2
+0.1
stress
Fusidic 0.001 mg/ml
N.D.
+0.9
-0.0
-0.2
+0.1
carbon source
D-Sorbitol (C)
N.D.
-0.2
+0.3
+0.4
+0.3
nitrogen source
L-Alanine (N)
N.D.
+1.0
-0.1
+0.1
-0.1
carbon source
pyruvate (C)
N.D.
+0.4
+0.2
+0.2
+0.3
carbon source
a-Ketoglutaric (C)
N.D.
+0.1
+0.6
+0.3
+0.1
pH
LB, pH10
N.D.
-0.1
+0.5
+0.3
+0.5
nitrogen source
L-Serine (N)
N.D.
+0.1
+0.3
+0.4
+0.4
carbon source
D,L-Lactate (C)
N.D.
+0.2
+0.2
+0.5
+0.4
motility
inner cut, R2A soft agar motility assay
N.D.
+0.5
+0.3
+0.2
+0.3
carbon source
succinate (C)
N.D.
+0.6
+0.2
+0.2
+0.4
nitrogen source
L-Isoleucine (N)
N.D.
+0.5
+0.1
+0.4
+0.3
pH
LB, pH10
N.D.
+0.0
+0.3
+0.5
+0.6
carbon source
L-Lactate (C)
N.D.
+0.6
+0.2
+0.5
+0.3
nitrogen source
L-Threonine (N)
N.D.
+0.8
+0.4
+0.4
+0.5
nitrogen source
Ammonium chloride (N)
N.D.
+1.3
+0.2
+0.8
+0.3
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