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Cofit
Protein
Homologs
Fitness for 5 genes in
Acidovorax sp. GW101-3H11
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Ac3H11_268 and Ac3H11_269 are separated by 229 nucleotides
Ac3H11_269 and Ac3H11_270 are separated by 54 nucleotides
Ac3H11_270 and Ac3H11_271 overlap by 32 nucleotides
Ac3H11_271 and Ac3H11_272 are separated by 10 nucleotides
Ac3H11_268 - Bona fide RidA/YjgF/TdcF/RutC subgroup, at 91,401 to 91,859
_268
Ac3H11_269 - Methyl-accepting chemotaxis protein I (serine chemoreceptor protein), at 92,089 to 93,855
_269
Ac3H11_270 - hypothetical protein, at 93,910 to 94,155
_270
Ac3H11_271 - Topoisomerase IV subunit A (EC 5.99.1.-), at 94,124 to 96,481
_271
Ac3H11_272 - Lytic transglycosylase, catalytic, at 96,492 to 97,355
_272
Group
Condition
Ac3H11
_268
Ac3H11
_269
Ac3H11
_270
Ac3H11
_271
Ac3H11
_272
nitrogen source
L-Serine (N)
-4.0
-0.0
-0.0
N.D.
-0.1
stress
perchlorate 10 mM
-2.8
+0.2
-0.3
N.D.
+0.2
nitrogen source
D-Alanine (N)
-2.3
-0.0
+0.3
N.D.
-0.4
stress
perchlorate 25 mM
-2.4
+0.2
-0.3
N.D.
+0.2
nitrogen source
L-Isoleucine (N)
-2.2
+0.1
-0.0
N.D.
-0.0
nitrogen source
Ammonium chloride (N)
-2.0
+0.2
-0.1
N.D.
-0.2
carbon source
D,L-Lactate (C)
-1.8
+0.1
-0.2
N.D.
+0.1
stress
copper (II) chloride 2 mM
-2.5
+0.1
+0.5
N.D.
+0.1
nitrogen source
L-Threonine (N)
-1.9
-0.0
+0.3
N.D.
-0.0
pH
LB, pH10
-0.9
+0.0
-0.6
N.D.
+0.1
nitrogen source
L-Proline (N)
-1.1
+0.0
-0.2
N.D.
-0.1
nitrogen source
L-Histidine (N)
-1.1
+0.1
-0.2
N.D.
-0.1
stress
nitrite 10 mM
-1.2
+0.1
-0.1
N.D.
-0.0
nitrogen source
L-Glutamine (N)
-1.3
+0.2
-0.2
N.D.
+0.1
carbon source
L-Malic (C)
-1.3
-0.0
+0.1
N.D.
+0.0
stress
Cisplatin 0.005 mg/ml
-1.8
+0.3
+0.2
N.D.
+0.0
carbon source
D-Glucose (C)
-1.1
+0.0
-0.2
N.D.
+0.0
carbon source
pyruvate (C)
-1.3
-0.0
+0.1
N.D.
+0.2
lb
LB
-1.1
-0.1
-0.4
N.D.
+0.7
nitrogen source
L-Leucine (N)
-0.9
+0.1
-0.1
N.D.
+0.1
carbon source
pyruvate (C)
-1.0
+0.0
+0.0
N.D.
+0.3
stress
Phosphomycin 0.06 mg/ml
-0.9
+0.2
+0.1
N.D.
-0.0
motility
inner cut, R2A soft agar motility assay
-0.3
+0.1
+0.4
N.D.
-0.8
lb
LB
-1.0
+0.1
+0.1
N.D.
+0.3
carbon source
D-Galactose (C)
-0.9
+0.1
+0.3
N.D.
+0.1
motility
inner cut, R2A soft agar motility assay
-0.7
-0.2
+0.2
N.D.
+0.4
carbon source
a-Ketoglutaric (C)
-0.7
+0.0
+0.2
N.D.
+0.3
stress
Phosphomycin 0.02 mg/ml
-0.6
+0.0
+0.4
N.D.
+0.3
stress
Chlorite 0.1 mM
+1.0
-0.1
+0.0
N.D.
-0.3
stress
D-Cycloserine 0.05 mg/ml
+1.2
-0.2
+0.3
N.D.
+0.1
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