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Cofit
Protein
Homologs
Fitness for 5 genes in
Acidovorax sp. GW101-3H11
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Ac3H11_2215 and Ac3H11_2216 are separated by 51 nucleotides
Ac3H11_2216 and Ac3H11_2217 overlap by 4 nucleotides
Ac3H11_2217 and Ac3H11_2218 are separated by 124 nucleotides
Ac3H11_2218 and Ac3H11_2219 are separated by 4 nucleotides
Ac3H11_2215 - Phosphomannomutase (EC 5.4.2.8), at 447,542 to 448,930
_2215
Ac3H11_2216 - Hydrolase, carbon-nitrogen family, at 448,982 to 449,779
_2216
Ac3H11_2217 - Lipid IVA 3-deoxy-D-manno-octulosonic acid transferase (EC 2.4.99.12) [often with (EC 2.4.99.13) also], at 449,776 to 451,143
_2217
Ac3H11_2218 - diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s), at 451,268 to 453,568
_2218
Ac3H11_2219 - Type I secretion outer membrane protein, TolC precursor, at 453,573 to 454,907
_2219
Group
Condition
Ac3H11
_2215
Ac3H11
_2216
Ac3H11
_2217
Ac3H11
_2218
Ac3H11
_2219
nitrogen source
L-Alanine (N)
N.D.
-0.1
N.D.
-0.1
-3.6
nitrogen source
Ammonium chloride (N)
N.D.
+0.6
N.D.
+0.1
-3.1
stress
nitrate 45 mM
N.D.
-0.2
N.D.
+0.1
-1.0
nitrogen source
Uridine (N)
N.D.
-0.4
N.D.
+0.0
-0.7
stress
copper (II) chloride 2 mM
N.D.
-0.5
N.D.
-0.2
-0.3
carbon source
L-Lactate (C)
N.D.
-0.6
N.D.
+0.1
-0.5
nitrogen source
L-Threonine (N)
N.D.
+0.7
N.D.
+0.1
-1.6
motility
inner cut, R2A soft agar motility assay
N.D.
+0.1
N.D.
+0.0
-0.9
lb
LB
N.D.
+0.2
N.D.
-0.0
-0.8
nitrogen source
L-Isoleucine (N)
N.D.
+0.1
N.D.
+0.1
-0.7
carbon source
a-Ketoglutaric (C)
N.D.
-0.8
N.D.
+0.1
+0.3
stress
nitrate 100 mM
N.D.
+0.3
N.D.
+0.0
-0.8
stress
D-Cycloserine 0.05 mg/ml
N.D.
-0.1
N.D.
+0.2
-0.6
stress
Cisplatin 0.0025 mg/ml
N.D.
-0.5
N.D.
-0.1
+0.4
stress
Phosphomycin 0.02 mg/ml
N.D.
-0.5
N.D.
+0.2
+0.1
carbon source
L-Malic (C)
N.D.
-0.6
N.D.
+0.1
+0.5
phage
phage 93.2
N.D.
-0.6
N.D.
+0.2
+0.6
stress
Cisplatin 0.005 mg/ml
N.D.
+0.5
N.D.
+0.5
-0.8
nitrogen source
L-Leucine (N)
N.D.
+0.6
N.D.
+0.2
-0.4
stress
Cobalt chloride 0.32 mM
N.D.
-0.3
N.D.
+0.1
+0.5
pH
LB, pH10
N.D.
+0.5
N.D.
+0.3
-0.4
pH
LB, pH10
N.D.
+0.3
N.D.
+0.4
-0.2
lb
LB
N.D.
+0.2
N.D.
-0.2
+0.5
lb
LB
N.D.
-0.3
N.D.
+0.0
+0.9
nitrogen source
L-tyrosine (N)
N.D.
+0.0
N.D.
+0.2
+0.7
carbon source
D-Mannose (C)
N.D.
+0.2
N.D.
+0.2
+0.5
stress
nitrate 20 mM
N.D.
+0.4
N.D.
+0.2
+0.4
carbon source
D-Galactose (C)
N.D.
+0.3
N.D.
+0.0
+0.8
stress
Bacitracin 0.008 mg/ml
N.D.
+0.3
N.D.
+0.1
+0.8
stress
Nickel (II) chloride 0.8 mM
N.D.
+0.4
N.D.
+0.2
+0.6
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