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Cofit
Protein
Homologs
Fitness for 5 genes in
Acidovorax sp. GW101-3H11
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Top 30 experiments (either direction), sorted by average fitness
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500 nt
Ac3H11_1623 and Ac3H11_1624 are separated by 219 nucleotides
Ac3H11_1624 and Ac3H11_1625 are separated by 84 nucleotides
Ac3H11_1625 and Ac3H11_1626 overlap by 11 nucleotides
Ac3H11_1626 and Ac3H11_1627 are separated by 40 nucleotides
Ac3H11_1623 - L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3)
(from data)
, at 205,621 to 206,793
_1623
Ac3H11_1624 - diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s), at 207,013 to 209,295
_1624
Ac3H11_1625 - Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-), at 209,380 to 211,749
_1625
Ac3H11_1626 - hypothetical protein, at 211,739 to 212,047
_1626
Ac3H11_1627 - hypothetical protein, at 212,088 to 212,468
_1627
Group
Condition
Ac3H11
_1623
Ac3H11
_1624
Ac3H11
_1625
Ac3H11
_1626
Ac3H11
_1627
carbon source
L-Lactate (C)
-5.8
+0.1
+0.2
-0.6
+0.1
carbon source
L-Lactate (C)
-5.4
+0.1
+0.0
+0.2
+0.3
carbon source
L-Lactate (C)
-4.7
+0.0
+0.0
-0.4
+0.3
carbon source
D,L-Lactate (C)
-2.2
+0.0
-0.2
-0.1
-0.0
stress
Cisplatin 0.005 mg/ml
-0.1
-0.0
-0.3
-1.6
-0.1
carbon source
D,L-Lactate (C)
-2.4
+0.1
+0.0
+0.1
+0.1
carbon source
D,L-Lactate (C)
-1.8
+0.1
+0.2
-0.2
-0.1
phage
phage 93.2
-0.5
+0.3
-0.3
-1.0
-0.1
stress
Bacitracin 0.016 mg/ml
+0.1
+0.0
-0.3
-1.0
-0.2
carbon source
a-Ketoglutaric (C)
-0.2
+0.1
+0.3
-1.1
-0.5
stress
Dimethyl Sulfoxide 6 vol%
-0.4
-0.1
-0.4
-0.5
+0.1
stress
copper (II) chloride 2 mM
-0.1
-0.1
+0.4
-1.3
+0.1
stress
Chlorite 0.1 mM
-0.4
-0.2
-0.5
-0.0
+0.4
nitrogen source
Ammonium chloride (N)
-0.6
+0.2
-0.2
-0.5
+0.4
nitrogen source
L-Threonine (N)
-0.7
+0.2
-0.0
-0.4
+0.3
carbon source
succinate (C)
-0.2
+0.1
+0.3
-0.7
+0.3
stress
Nickel (II) chloride 0.6 mM
-0.1
+0.2
-0.3
-0.4
+0.4
pH
LB, pH6
+0.2
+0.2
+0.2
-0.9
+0.1
carbon source
succinate (C)
-0.4
-0.2
-0.3
+0.9
+0.1
nitrogen source
L-Alanine (N)
-0.3
-0.1
-0.1
+0.4
+0.5
stress
Paraquat dichloride 0.01 mg/ml
-0.5
+0.3
+0.1
+0.7
+0.0
nitrogen source
Uridine (N)
-0.4
+0.6
+0.3
+0.6
-0.0
pH
LB, pH10
+0.1
-0.1
+0.3
+0.6
+0.3
stress
Cobalt chloride 0.16 mM
+0.5
+0.3
-0.1
+0.5
-0.0
nitrogen source
D-Alanine (N)
-0.2
+0.4
+0.5
+0.2
+0.3
carbon source
a-Ketoglutaric (C)
-0.1
+0.1
+0.4
+0.8
+0.3
motility
inner cut, R2A soft agar motility assay
-0.2
+1.7
-0.4
+0.4
+0.1
carbon source
D-Ribose (C)
+0.4
+0.1
+0.2
+0.7
+0.2
motility
inner cut, R2A soft agar motility assay
-0.2
+2.4
-0.2
-0.1
+0.3
motility
inner cut, R2A soft agar motility assay
+0.3
+2.7
-0.6
+1.2
+0.2
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