Gene info for SMc02237 in Sinorhizobium meliloti 1021

Updated annotation (from data): DNA damage response helicase, ligase-associated
Rationale: Conserved and specific phenotype: important for resisting cisplatin. Related to Lhr, which is either a DNA:DNA or DNA:RNA helicase, but lacks the long C-terminal extension that might have a regulatory role (see putative winged helix domain in E. coli lhr). This is also related to the archael protein saci_1500, which has also been linked to DNA damage response, as a mutant is sensitive to UV (PMID: 26148716)
Original annotation: ATP-dependent helicase
Type 1: Protein-coding gene
Located on scaffold NC_003047, - strand, nucleotides 600,851 to 603,400
See nucleotide sequence around SMc02237 or for all of scaffold NC_003047

Other databases: NCBI, IMG: 637181326, uniprot: Q92S82

Nearby Genes

500 ntSMc02231 and SMc02232 are separated by 337 nucleotidesSMc02232 and SMc02234 overlap by 1 nucleotidesSMc02234 and SMc02235 are separated by 98 nucleotidesSMc02235 and SMc02236 are separated by 119 nucleotidesSMc02236 and SMc02237 are separated by 243 nucleotidesSMc02237 and SMc02238 are separated by 107 nucleotidesSMc02238 and SMc02239 are separated by 38 nucleotidesSMc02239 and SMc02240 are separated by 29 nucleotidesSMc02240 and SMc02241 are separated by 108 nucleotidesSMc02241 and SMc02242 are separated by 15 nucleotides SMc02231: SMc02231 - hypothetical protein, at 596,668 to 597,357 SMc02231 SMc02232: SMc02232 - hypothetical protein, at 597,695 to 598,621 SMc02232 SMc02234: SMc02234 - hypothetical protein, at 598,621 to 599,424 SMc02234 SMc02235: SMc02235 - transcriptional regulator, at 599,523 to 599,759 SMc02235 SMc02236: SMc02236 - DNA repair nuclease, ligase-associated (TIGR04123) (from data), at 599,879 to 600,607 SMc02236 SMc02237: SMc02237 - DNA damage response helicase, ligase-associated (from data), at 600,851 to 603,400 SMc02237 SMc02238: SMc02238 - hypothetical protein, at 603,508 to 604,014 SMc02238 SMc02239: SMc02239 - hypothetical protein, at 604,053 to 604,514 SMc02239 SMc02240: SMc02240 - hypothetical protein, at 604,544 to 605,179 SMc02240 SMc02241: SMc02241 - hypothetical protein, at 605,288 to 606,226 SMc02241 SMc02242: SMc02242 - hypothetical protein, at 606,242 to 606,640 SMc02242
Locus Name Description Strand Phenotype
SMc02231 SMc02231 hypothetical protein + insig.
SMc02232 SMc02232 hypothetical protein + strong
SMc02234 SMc02234 hypothetical protein + sig.
SMc02235 SMc02235 transcriptional regulator + insig.
SMc02236 SMc02236 DNA repair nuclease, ligase-associated (TIGR04123) (from data) - strong
SMc02237 SMc02237 DNA damage response helicase, ligase-associated (from data) - strong
SMc02238 SMc02238 hypothetical protein + insig.
SMc02239 SMc02239 hypothetical protein + insig.
SMc02240 SMc02240 hypothetical protein - strong
SMc02241 SMc02241 hypothetical protein - insig.
SMc02242 SMc02242 hypothetical protein + insig.

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