Gene info for RR42_RS28295 in Cupriavidus basilensis FW507-4G11

Updated annotation (from data): 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29)
Rationale: Specifically important for utilizing L-Threonine. Automated validation from mutant phenotype: the predicted function (AKBLIG-RXN) was linked to the condition via a MetaCyc pathway. This annotation was also checked manually.
Original annotation: 2-amino-3-ketobutyrate CoA ligase
Type 1: Protein-coding gene
Located on scaffold NZ_CP010537, + strand, nucleotides 1,708,250 to 1,709,452
See nucleotide sequence around RR42_RS28295 or for all of scaffold NZ_CP010537

Other databases: NCBI, uniprot: A0A0C4YMA5

Nearby Genes

500 ntRR42_RS28270 and RR42_RS28275 are separated by 167 nucleotidesRR42_RS28275 and RR42_RS28280 are separated by 246 nucleotidesRR42_RS28280 and RR42_RS28285 are separated by 5 nucleotidesRR42_RS28285 and RR42_RS28290 are separated by 486 nucleotidesRR42_RS28290 and RR42_RS28295 are separated by 88 nucleotidesRR42_RS28295 and RR42_RS28300 overlap by 4 nucleotidesRR42_RS28300 and RR42_RS28305 are separated by 474 nucleotidesRR42_RS28305 and RR42_RS28315 are separated by 1130 nucleotidesRR42_RS28315 and RR42_RS28320 are separated by 181 nucleotidesRR42_RS28320 and RR42_RS28325 are separated by 223 nucleotides RR42_RS28270: RR42_RS28270 - TetR family transcriptional regulator, at 1,702,836 to 1,703,432 _RS28270 RR42_RS28275: RR42_RS28275 - short-chain dehydrogenase, at 1,703,600 to 1,704,364 _RS28275 RR42_RS28280: RR42_RS28280 - ubiquinol oxidase subunit II, at 1,704,611 to 1,705,618 _RS28280 RR42_RS28285: RR42_RS28285 - cytochrome D ubiquinol oxidase subunit I, at 1,705,624 to 1,707,078 _RS28285 RR42_RS28290: RR42_RS28290 - DNA-binding protein, at 1,707,565 to 1,708,161 _RS28290 RR42_RS28295: RR42_RS28295 - 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) (from data), at 1,708,250 to 1,709,452 _RS28295 RR42_RS28300: RR42_RS28300 - L-threonine 3-dehydrogenase (EC 1.1.1.103) (from data), at 1,709,449 to 1,710,423 _RS28300 RR42_RS28305: RR42_RS28305 - L-threonine:H+ symporter (from data), at 1,710,898 to 1,712,316 _RS28305 RR42_RS28315: RR42_RS28315 - GntR family transcriptional regulator, at 1,713,447 to 1,714,115 _RS28315 RR42_RS28320: RR42_RS28320 - porin, at 1,714,297 to 1,715,367 _RS28320 RR42_RS28325: RR42_RS28325 - 3-hydroxyacyl-CoA dehydrogenase, at 1,715,591 to 1,716,958 _RS28325
Locus Name Description Strand Phenotype
RR42_RS28270 RR42_RS28270 TetR family transcriptional regulator - insig.
RR42_RS28275 RR42_RS28275 short-chain dehydrogenase + insig.
RR42_RS28280 RR42_RS28280 ubiquinol oxidase subunit II - insig.
RR42_RS28285 RR42_RS28285 cytochrome D ubiquinol oxidase subunit I - insig.
RR42_RS28290 RR42_RS28290 DNA-binding protein - strong
RR42_RS28295 RR42_RS28295 2-amino-3-ketobutyrate coenzyme A ligase (EC 2.3.1.29) (from data) + strong
RR42_RS28300 RR42_RS28300 L-threonine 3-dehydrogenase (EC 1.1.1.103) (from data) + strong
RR42_RS28305 RR42_RS28305 L-threonine:H+ symporter (from data) + sig.
RR42_RS28315 RR42_RS28315 GntR family transcriptional regulator + sig.
RR42_RS28320 RR42_RS28320 porin - insig.
RR42_RS28325 RR42_RS28325 3-hydroxyacyl-CoA dehydrogenase - insig.

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