Gene info for RR42_RS21285 in Cupriavidus basilensis FW507-4G11

Updated annotation (from data): L-lactate dehydrogenase, LutB subunit
Rationale: Specifically important for utilization of L-lactate or D,L-lactate. (Also important on various nitrogen sources with lactate as the carbon source.) This is related to the LutABC system from Bacillus subtilis (PMC3347220, PMC2668416).
Original annotation: (Fe-S)-binding protein
Type 1: Protein-coding gene
Located on scaffold NZ_CP010537, - strand, nucleotides 102,111 to 103,541
See nucleotide sequence around RR42_RS21285 or for all of scaffold NZ_CP010537

Other databases: NCBI, uniprot: A0A0C4Y8G6

Nearby Genes

500 ntRR42_RS21260 and RR42_RS21265 are separated by 106 nucleotidesRR42_RS21265 and RR42_RS21270 are separated by 180 nucleotidesRR42_RS21270 and RR42_RS21275 are separated by 69 nucleotidesRR42_RS21275 and RR42_RS21280 are separated by 51 nucleotidesRR42_RS21280 and RR42_RS21285 are separated by 510 nucleotidesRR42_RS21285 and RR42_RS21290 are separated by 35 nucleotidesRR42_RS21290 and RR42_RS21295 overlap by 4 nucleotidesRR42_RS21295 and RR42_RS21300 are separated by 138 nucleotidesRR42_RS21300 and RR42_RS21305 are separated by 179 nucleotidesRR42_RS21305 and RR42_RS21310 are separated by 240 nucleotides RR42_RS21260: RR42_RS21260 - isovaleryl-CoA dehydrogenase, at 95,066 to 96,862 _RS21260 RR42_RS21265: RR42_RS21265 - ABC transporter substrate-binding protein, at 96,969 to 97,949 _RS21265 RR42_RS21270: RR42_RS21270 - phenylacetic acid degradation-like protein, at 98,130 to 98,585 _RS21270 RR42_RS21275: RR42_RS21275 - carnitine dehydratase, at 98,655 to 99,806 _RS21275 RR42_RS21280: RR42_RS21280 - L-lactate permease, at 99,858 to 101,600 _RS21280 RR42_RS21285: RR42_RS21285 - L-lactate dehydrogenase, LutB subunit (from data), at 102,111 to 103,541 _RS21285 RR42_RS21290: RR42_RS21290 - L-lactate dehydrogenase, LutC subunit (from data), at 103,577 to 104,281 _RS21290 RR42_RS21295: RR42_RS21295 - L-lactate dehydrogenase, LutA subunit (from data), at 104,278 to 105,066 _RS21295 RR42_RS21300: RR42_RS21300 - GntR family transcriptional regulator, at 105,205 to 105,930 _RS21300 RR42_RS21305: RR42_RS21305 - membrane protein, at 106,110 to 107,147 _RS21305 RR42_RS21310: RR42_RS21310 - hypothetical protein, at 107,388 to 108,449 _RS21310
Locus Name Description Strand Phenotype
RR42_RS21260 RR42_RS21260 isovaleryl-CoA dehydrogenase + cofit
RR42_RS21265 RR42_RS21265 ABC transporter substrate-binding protein + insig.
RR42_RS21270 RR42_RS21270 phenylacetic acid degradation-like protein + no data
RR42_RS21275 RR42_RS21275 carnitine dehydratase + sig.
RR42_RS21280 RR42_RS21280 L-lactate permease - strong
RR42_RS21285 RR42_RS21285 L-lactate dehydrogenase, LutB subunit (from data) - strong
RR42_RS21290 RR42_RS21290 L-lactate dehydrogenase, LutC subunit (from data) - strong
RR42_RS21295 RR42_RS21295 L-lactate dehydrogenase, LutA subunit (from data) - cofit
RR42_RS21300 RR42_RS21300 GntR family transcriptional regulator + strong
RR42_RS21305 RR42_RS21305 membrane protein - insig.
RR42_RS21310 RR42_RS21310 hypothetical protein - insig.

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