Gene info for Pf6N2E2_496 in Pseudomonas fluorescens FW300-N2E2

Updated annotation (from data): Dihydropyrimidine dehydrogenase (NADP(+)) (EC 1.3.1.2)
Rationale: Specifically important for utilizing Cytosine. Automated validation from mutant phenotype: the predicted function (1.3.1.2) was linked to the condition via a SEED subsystem. This annotation was also checked manually.
Original annotation: Dihydropyrimidine dehydrogenase [NADP+] (EC 1.3.1.2)
Type 1: Protein-coding gene
Located on scaffold unitig_0|quiver.unitig_1|quiver|pilon, - strand, nucleotides 562,747 to 564,021
See nucleotide sequence around Pf6N2E2_496 or for all of scaffold unitig_0|quiver.unitig_1|quiver|pilon

Other databases: refseq: TK06_RS02480, uniprot: A0A159ZT50

Nearby Genes

500 ntPf6N2E2_491 and Pf6N2E2_492 are separated by 273 nucleotidesPf6N2E2_492 and Pf6N2E2_493 are separated by 55 nucleotidesPf6N2E2_493 and Pf6N2E2_494 are separated by 149 nucleotidesPf6N2E2_494 and Pf6N2E2_495 are separated by 29 nucleotidesPf6N2E2_495 and Pf6N2E2_496 are separated by 183 nucleotidesPf6N2E2_496 and Pf6N2E2_497 are separated by 0 nucleotidesPf6N2E2_497 and Pf6N2E2_498 are separated by 183 nucleotidesPf6N2E2_498 and Pf6N2E2_499 are separated by 608 nucleotidesPf6N2E2_499 and Pf6N2E2_500 are separated by 78 nucleotidesPf6N2E2_500 and Pf6N2E2_501 are separated by 84 nucleotides Pf6N2E2_491 - hypothetical protein, at 558,482 to 558,835 _491 Pf6N2E2_492 - Transcriptional regulator RutR of pyrimidine catabolism (TetR family), at 559,109 to 559,729 _492 Pf6N2E2_493 - YD repeat protein, at 559,785 to 560,831 _493 Pf6N2E2_494 - Transcriptional regulator RutR of pyrimidine catabolism (TetR family), at 560,981 to 561,418 _494 Pf6N2E2_495 - YD repeat protein, at 561,448 to 562,563 _495 Pf6N2E2_496 - Dihydropyrimidine dehydrogenase (NADP(+)) (EC 1.3.1.2) (from data), at 562,747 to 564,021 _496 Pf6N2E2_497 - Pyridine nucleotide-disulphide oxidoreductase associated with reductive pyrimidine catabolism, at 564,022 to 565,389 _497 Pf6N2E2_498 - Dihydropyrimidinase (EC 3.5.2.2) (from data), at 565,573 to 567,012 _498 Pf6N2E2_499 - Possible pyrimidine permease in reductive pathway, at 567,621 to 569,099 _499 Pf6N2E2_500 - Beta-ureidopropionase (EC 3.5.1.6), at 569,178 to 570,461 _500 Pf6N2E2_501 - Sensory box transcriptional regulator, LuxR family, at 570,546 to 572,030 _501
Locus Name Description Strand Phenotype
Pf6N2E2_491 hypothetical protein + insig.
Pf6N2E2_492 Transcriptional regulator RutR of pyrimidine catabolism (TetR family) + insig.
Pf6N2E2_493 YD repeat protein - insig.
Pf6N2E2_494 Transcriptional regulator RutR of pyrimidine catabolism (TetR family) + insig.
Pf6N2E2_495 YD repeat protein - sig.
Pf6N2E2_496 Dihydropyrimidine dehydrogenase (NADP(+)) (EC 1.3.1.2) (from data) - strong
Pf6N2E2_497 Pyridine nucleotide-disulphide oxidoreductase associated with reductive pyrimidine catabolism - strong
Pf6N2E2_498 Dihydropyrimidinase (EC 3.5.2.2) (from data) - strong
Pf6N2E2_499 Possible pyrimidine permease in reductive pathway + strong
Pf6N2E2_500 Beta-ureidopropionase (EC 3.5.1.6) + sig.
Pf6N2E2_501 Sensory box transcriptional regulator, LuxR family + insig.

Or browse nearby genes

Or see the comparative fitness browser