Updated annotation (from data): Urocanate hydratase (EC 4.2.1.49) Rationale: Specifically important for utilizing L-Histidine. Automated validation from mutant phenotype: the predicted function (UROCANATE-HYDRATASE-RXN) was linked to the condition via a MetaCyc pathway. This annotation was also checked manually. Original annotation: Urocanate hydratase (EC 4.2.1.49) Type 1: Protein-coding gene Located on scaffold unitig_0|quiver.unitig_1|quiver|pilon, - strand, nucleotides 4,433,369 to 4,435,057 See nucleotide sequence around Pf6N2E2_3805 or for all of scaffold unitig_0|quiver.unitig_1|quiver|pilon
Other databases: refseq: TK06_RS19025, uniprot: A0A160A2I5
Nearby Genes
500 nt Pf6N2E2_3800 and Pf6N2E2_3801 are separated by 174 nucleotides Pf6N2E2_3801 and Pf6N2E2_3802 overlap by 4 nucleotides Pf6N2E2_3802 and Pf6N2E2_3803 are separated by 69 nucleotides Pf6N2E2_3803 and Pf6N2E2_3804 are separated by 70 nucleotides Pf6N2E2_3804 and Pf6N2E2_3805 are separated by 152 nucleotides Pf6N2E2_3805 and Pf6N2E2_3806 are separated by 925 nucleotides Pf6N2E2_3806 and Pf6N2E2_3807 overlap by 4 nucleotides Pf6N2E2_3807 and Pf6N2E2_3808 are separated by 104 nucleotides Pf6N2E2_3808 and Pf6N2E2_3809 are separated by 121 nucleotides Pf6N2E2_3809 and Pf6N2E2_3810 are separated by 109 nucleotides
Pf6N2E2_3800 - Histidine ammonia-lyase (EC 4.3.1.3), at 4,427,265 to 4,428,788
_3800
Pf6N2E2_3801 - Histidine ABC transporter, ATP-binding protein (TC 3.A.1), at 4,428,963 to 4,429,793
_3801
Pf6N2E2_3802 - Histidine ABC transporter, permease protein (TC 3.A.1), at 4,429,790 to 4,430,641
_3802
Pf6N2E2_3803 - Histidine ABC transporter, histidine-binding protein (TC 3.A.1), at 4,430,711 to 4,431,679
_3803
Pf6N2E2_3804 - Cytosine/purine/uracil/thiamine/allantoin permease family protein, at 4,431,750 to 4,433,216
_3804
Pf6N2E2_3805 - Urocanate hydratase (EC 4.2.1.49) (from data) , at 4,433,369 to 4,435,057
_3805
Pf6N2E2_3806 - Conserved hypothetical protein (perhaps related to histidine degradation), at 4,435,983 to 4,436,552
_3806
Pf6N2E2_3807 - Histidine utilization repressor, at 4,436,549 to 4,437,298
_3807
Pf6N2E2_3808 - Formiminoglutamic iminohydrolase (EC 3.5.3.13) (from data) , at 4,437,403 to 4,438,767
_3808
Pf6N2E2_3809 - Outer membrane lipoprotein Blc, at 4,438,889 to 4,439,455
_3809
Pf6N2E2_3810 - Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1), at 4,439,565 to 4,439,819
_3810
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