Gene info for Pf6N2E2_2192 in Pseudomonas fluorescens FW300-N2E2

Updated annotation (from data): 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4)
Rationale: Specifically important for utilizing L-Leucine. Automated validation from mutant phenotype: the predicted function (6.4.1.4) was linked to the condition via a SEED subsystem. This annotation was also checked manually.
Original annotation: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
Type 1: Protein-coding gene
Located on scaffold unitig_0|quiver.unitig_1|quiver|pilon, + strand, nucleotides 2,597,887 to 2,599,494
See nucleotide sequence around Pf6N2E2_2192 or for all of scaffold unitig_0|quiver.unitig_1|quiver|pilon

Other databases: refseq: TK06_RS11060, uniprot: A0A165Z6X2

Nearby Genes

500 ntPf6N2E2_2187 and Pf6N2E2_2188 are separated by 197 nucleotidesPf6N2E2_2188 and Pf6N2E2_2189 are separated by 92 nucleotidesPf6N2E2_2189 and Pf6N2E2_2190 are separated by 653 nucleotidesPf6N2E2_2190 and Pf6N2E2_2191 are separated by 198 nucleotidesPf6N2E2_2191 and Pf6N2E2_2192 are separated by 11 nucleotidesPf6N2E2_2192 and Pf6N2E2_2193 are separated by 13 nucleotidesPf6N2E2_2193 and Pf6N2E2_2194 overlap by 4 nucleotidesPf6N2E2_2194 and Pf6N2E2_2195 are separated by 29 nucleotidesPf6N2E2_2195 and Pf6N2E2_2196 are separated by 122 nucleotidesPf6N2E2_2196 and Pf6N2E2_2197 are separated by 499 nucleotides Pf6N2E2_2187 - Transcriptional regulator, LysR family, at 2,591,642 to 2,592,571 _2187 Pf6N2E2_2188 - Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family, at 2,592,769 to 2,593,170 _2188 Pf6N2E2_2189 - Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4), at 2,593,263 to 2,594,162 _2189 Pf6N2E2_2190 - Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3), at 2,594,816 to 2,596,513 _2190 Pf6N2E2_2191 - Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) (from data), at 2,596,712 to 2,597,875 _2191 Pf6N2E2_2192 - 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data), at 2,597,887 to 2,599,494 _2192 Pf6N2E2_2193 - Methylglutaconyl-CoA hydratase (EC 4.2.1.18) (from data), at 2,599,508 to 2,600,326 _2193 Pf6N2E2_2194 - 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data), at 2,600,323 to 2,602,272 _2194 Pf6N2E2_2195 - cI, at 2,602,302 to 2,602,958 _2195 Pf6N2E2_2196 - FIG00953347: hypothetical protein, at 2,603,081 to 2,603,422 _2196 Pf6N2E2_2197 - Predicted carboxypeptidase, at 2,603,922 to 2,605,067 _2197
Locus Name Description Strand Phenotype
Pf6N2E2_2187 Transcriptional regulator, LysR family + insig.
Pf6N2E2_2188 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family + strong
Pf6N2E2_2189 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) + strong
Pf6N2E2_2190 Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) - insig.
Pf6N2E2_2191 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) (from data) + strong
Pf6N2E2_2192 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) + strong
Pf6N2E2_2193 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) (from data) + strong
Pf6N2E2_2194 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data) + strong
Pf6N2E2_2195 cI - sig.
Pf6N2E2_2196 FIG00953347: hypothetical protein + insig.
Pf6N2E2_2197 Predicted carboxypeptidase + insig.

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