Updated annotation (from data): DNA damage response nuclease Rationale: Conserved and specific phenotype: important for resisting cisplatin. Contains a VRR-NUC domain that is predicted to have nuclease activity. Original annotation: Hypothetical protein, restriction endonuclease-like VRR-NUC domain Type 1: Protein-coding gene Located on scaffold unitig_0|quiver.unitig_1|quiver|pilon, - strand, nucleotides 1,434,468 to 1,436,138 See nucleotide sequence around Pf6N2E2_1226 or for all of scaffold unitig_0|quiver.unitig_1|quiver|pilon
Other databases: refseq: TK06_RS06175, uniprot: A0A159ZSZ5
Nearby Genes
500 nt Pf6N2E2_1221 and Pf6N2E2_1222 are separated by 148 nucleotides Pf6N2E2_1222 and Pf6N2E2_1223 are separated by 153 nucleotides Pf6N2E2_1223 and Pf6N2E2_1224 are separated by 114 nucleotides Pf6N2E2_1224 and Pf6N2E2_1225 are separated by 49 nucleotides Pf6N2E2_1225 and Pf6N2E2_1226 overlap by 4 nucleotides Pf6N2E2_1226 and Pf6N2E2_1227 are separated by 220 nucleotides Pf6N2E2_1227 and Pf6N2E2_1228 are separated by 128 nucleotides Pf6N2E2_1228 and Pf6N2E2_1229 are separated by 169 nucleotides Pf6N2E2_1229 and Pf6N2E2_1230 are separated by 68 nucleotides Pf6N2E2_1230 and Pf6N2E2_1231 overlap by 7 nucleotides
Pf6N2E2_1221 - sodium/hydrogen exchanger family protein, at 1,427,660 to 1,428,997
_1221
Pf6N2E2_1222 - FIG00954310: hypothetical protein, at 1,429,146 to 1,429,682
_1222
Pf6N2E2_1223 - Amino acid transporters, at 1,429,836 to 1,430,066
_1223
Pf6N2E2_1224 - Two-component hybrid sensor and regulator, at 1,430,181 to 1,432,109
_1224
Pf6N2E2_1225 - DinG family ATP-dependent helicase CPE1197, at 1,432,159 to 1,434,471
_1225
Pf6N2E2_1226 - DNA damage response nuclease (from data) , at 1,434,468 to 1,436,138
_1226
Pf6N2E2_1227 - FIG00955097: hypothetical protein, at 1,436,359 to 1,436,583
_1227
Pf6N2E2_1228 - Lipase (EC 3.1.1.3), at 1,436,712 to 1,438,565
_1228
Pf6N2E2_1229 - Serine protease homologue, at 1,438,735 to 1,441,827
_1229
Pf6N2E2_1230 - Ferric iron ABC transporter, permease protein, at 1,441,896 to 1,442,084
_1230
Pf6N2E2_1231 - ABC-type protease exporter, outer membrane component PrtF/AprF, at 1,442,078 to 1,443,427
_1231
Or browse nearby genes
Or see the comparative fitness browser