Updated annotation (from data): 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) Rationale: Important for fitness in most defined media. Semi-automated annotation based on the auxotrophic phenotype and a hit to HMM TIGR00007. Original annotation: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Type 1: Protein-coding gene Located on scaffold NC_014323, - strand, nucleotides 4,657,853 to 4,658,650 See nucleotide sequence around HSERO_RS20320 or for all of scaffold NC_014323
Other databases: NCBI , uniprot: D8ISW8
Nearby Genes
500 nt HSERO_RS20295 and HSERO_RS20300 are separated by 73 nucleotides HSERO_RS20300 and HSERO_RS20305 are separated by 49 nucleotides HSERO_RS20305 and HSERO_RS20310 overlap by 4 nucleotides HSERO_RS20310 and HSERO_RS20315 overlap by 4 nucleotides HSERO_RS20315 and HSERO_RS20320 are separated by 1 nucleotides HSERO_RS20320 and HSERO_RS20325 are separated by 76 nucleotides HSERO_RS20325 and HSERO_RS20330 are separated by 61 nucleotides HSERO_RS20330 and HSERO_RS20335 are separated by 73 nucleotides HSERO_RS20335 and HSERO_RS20340 overlap by 26 nucleotides HSERO_RS20340 and HSERO_RS20345 are separated by 4 nucleotides
HSERO_RS20295: HSERO_RS20295 - preprotein translocase subunit TatA, at 4,655,548 to 4,655,751
_RS20295
HSERO_RS20300: HSERO_RS20300 - HIT family hydrolase, at 4,655,825 to 4,656,205
_RS20300
HSERO_RS20305: HSERO_RS20305 - phosphoribosyl-ATP pyrophosphatase, at 4,656,255 to 4,656,593
_RS20305
HSERO_RS20310: HSERO_RS20310 - phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) (from data) , at 4,656,590 to 4,657,090
_RS20310
HSERO_RS20315: HSERO_RS20315 - imidazole glycerol phosphate synthase, at 4,657,087 to 4,657,851
_RS20315
HSERO_RS20320: HSERO_RS20320 - 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) , at 4,657,853 to 4,658,650
_RS20320
HSERO_RS20325: HSERO_RS20325 - IGP synthase, amidotransferase subunit (EC 4.3.2.10) (from data) , at 4,658,727 to 4,659,365
_RS20325
HSERO_RS20330: HSERO_RS20330 - imidazoleglycerol-phosphate dehydratase, at 4,659,427 to 4,660,023
_RS20330
HSERO_RS20335: HSERO_RS20335 - histidinol-phosphate aminotransferase, at 4,660,097 to 4,661,215
_RS20335
HSERO_RS20340: HSERO_RS20340 - DNA methylase N-4, at 4,661,190 to 4,662,020
_RS20340
HSERO_RS20345: HSERO_RS20345 - histidinol dehydrogenase, at 4,662,025 to 4,663,341
_RS20345
Or browse nearby genes
Or see the comparative fitness browser