Gene info for H281DRAFT_00361 in Paraburkholderia bryophila 376MFSha3.1

Updated annotation (from data): (3S)-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.35) / enoyl-CoA hydratase domain
Rationale: H281DRAFT_00361 is specifically important for phenylacetate utilization via the oxygenase pathway. This pathway require a (3S)-hydroxyadipyl-CoA dehydrogenase (forming 3-oxoadipyl-CoA), which is probably provided by the aldehyde dehydrogenase domain of H281DRAFT_00361. H281DRAFT_00361 is 49% identical to PimB from Rhodopseudomonas palustris; the pim operon is involved in dicarboxylic fatty acid degradation (PMID:15758219), which is consistent with activity on (3S)-hydroxyadipyl-CoA. H281DRAFT_00361 also has an enoyl-CoA hydratase domain, whose role (if any) in phenylacetate utilization is not clear.
Original annotation: short chain enoyl-CoA hydratase /3-hydroxyacyl-CoA dehydrogenase
Type 1: Protein-coding gene
Located on scaffold H281DRAFT_scaffold00001.1, - strand, nucleotides 394,803 to 396,923
See nucleotide sequence around H281DRAFT_00361 or for all of scaffold H281DRAFT_scaffold00001.1

Other databases: NCBI

Nearby Genes

500 ntH281DRAFT_00356 and H281DRAFT_00357 are separated by 43 nucleotidesH281DRAFT_00357 and H281DRAFT_00358 are separated by 217 nucleotidesH281DRAFT_00358 and H281DRAFT_00359 are separated by 167 nucleotidesH281DRAFT_00359 and H281DRAFT_00360 are separated by 12 nucleotidesH281DRAFT_00360 and H281DRAFT_00361 are separated by 46 nucleotidesH281DRAFT_00361 and H281DRAFT_00362 are separated by 147 nucleotidesH281DRAFT_00362 and H281DRAFT_00363 are separated by 172 nucleotidesH281DRAFT_00363 and H281DRAFT_00364 are separated by 84 nucleotidesH281DRAFT_00364 and H281DRAFT_00365 are separated by 29 nucleotidesH281DRAFT_00365 and H281DRAFT_00366 are separated by 240 nucleotides H281DRAFT_00356: H281DRAFT_00356 - acetolactate synthase, large subunit, at 388,873 to 390,738 _00356 H281DRAFT_00357: H281DRAFT_00357 - transcriptional regulator, ArsR family, at 390,782 to 391,081 _00357 H281DRAFT_00358: H281DRAFT_00358 - Aldo/keto reductase, at 391,299 to 392,237 _00358 H281DRAFT_00359: H281DRAFT_00359 - Acyl-CoA dehydrogenase, at 392,405 to 393,535 _00359 H281DRAFT_00360: H281DRAFT_00360 - hypothetical protein, at 393,548 to 394,756 _00360 H281DRAFT_00361: H281DRAFT_00361 - (3S)-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.35) / enoyl-CoA hydratase domain (from data), at 394,803 to 396,923 _00361 H281DRAFT_00362: H281DRAFT_00362 - transcriptional regulator, LysR family, at 397,071 to 397,979 _00362 H281DRAFT_00363: H281DRAFT_00363 - hypothetical protein, at 398,152 to 398,340 _00363 H281DRAFT_00364: H281DRAFT_00364 - hypothetical protein, at 398,425 to 398,805 _00364 H281DRAFT_00365: H281DRAFT_00365 - methyl-accepting chemotaxis sensory transducer with Cache sensor, at 398,835 to 400,634 _00365 H281DRAFT_00366: H281DRAFT_00366 - phospholipase C, at 400,875 to 402,986 _00366
Locus Name Description Strand Phenotype
H281DRAFT_00356 H281DRAFT_00356 acetolactate synthase, large subunit + insig.
H281DRAFT_00357 H281DRAFT_00357 transcriptional regulator, ArsR family + no data
H281DRAFT_00358 H281DRAFT_00358 Aldo/keto reductase + insig.
H281DRAFT_00359 H281DRAFT_00359 Acyl-CoA dehydrogenase - insig.
H281DRAFT_00360 H281DRAFT_00360 hypothetical protein - cofit
H281DRAFT_00361 H281DRAFT_00361 (3S)-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.35) / enoyl-CoA hydratase domain (from data) - strong
H281DRAFT_00362 H281DRAFT_00362 transcriptional regulator, LysR family + sig.
H281DRAFT_00363 H281DRAFT_00363 hypothetical protein + no data
H281DRAFT_00364 H281DRAFT_00364 hypothetical protein + no data
H281DRAFT_00365 H281DRAFT_00365 methyl-accepting chemotaxis sensory transducer with Cache sensor - no data
H281DRAFT_00366 H281DRAFT_00366 phospholipase C - insig.

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