Gene info for Ga0059261_2929 in Sphingomonas koreensis DSMZ 15582

Updated annotation (from data): oxygen-dependent methionine synthase, methyltransferase component MesD
Rationale: Required for methionine synthesis in the absence of cobalamin. Contains the C-terminal domain of MetE (catalytic and homocysteine-binding) but not the N-terminal (folate-binding) domain. Requires MesX (Ga0059261_2928, DUF1852) and oxygen, but not 5-methyltetrahydrofolate. See https://doi.org/10.1101/2020.04.21.054031
Original annotation: methionine synthase (B12-independent) (EC 2.1.1.14)
Type 1: Protein-coding gene
Located on scaffold Ga0059261_unitig_0_quiver.1, + strand, nucleotides 3,037,215 to 3,038,243
See nucleotide sequence around Ga0059261_2929 or for all of scaffold Ga0059261_unitig_0_quiver.1

Other databases: NCBI, uniprot: A0A2M8WFA5

Nearby Genes

500 ntGa0059261_2924 and Ga0059261_2925 overlap by 4 nucleotidesGa0059261_2925 and Ga0059261_2926 overlap by 104 nucleotidesGa0059261_2926 and Ga0059261_2927 are separated by 376 nucleotidesGa0059261_2927 and Ga0059261_2928 are separated by 483 nucleotidesGa0059261_2928 and Ga0059261_2929 are separated by 30 nucleotidesGa0059261_2929 and Ga0059261_2930 are separated by 36 nucleotidesGa0059261_2930 and Ga0059261_2931 are separated by 25 nucleotidesGa0059261_2931 and Ga0059261_2932 are separated by 109 nucleotidesGa0059261_2932 and Ga0059261_2933 are separated by 100 nucleotidesGa0059261_2933 and Ga0059261_2934 overlap by 11 nucleotides Ga0059261_2924: Ga0059261_2924 - Transposase and inactivated derivatives, at 3,032,231 to 3,033,730 _2924 Ga0059261_2925: Ga0059261_2925 - DNA replication protein, at 3,033,727 to 3,034,557 _2925 Ga0059261_2926: Ga0059261_2926 - Domain of unknown function (DUF4102), at 3,034,454 to 3,035,215 _2926 Ga0059261_2927: Ga0059261_2927 - hypothetical protein, at 3,035,592 to 3,035,714 _2927 Ga0059261_2928: Ga0059261_2928 - oxygen-dependent methionine synthase, putative oxygenase component MesX (from data), at 3,036,198 to 3,037,184 _2928 Ga0059261_2929: Ga0059261_2929 - oxygen-dependent methionine synthase, methyltransferase component MesD (from data), at 3,037,215 to 3,038,243 _2929 Ga0059261_2930: Ga0059261_2930 - Predicted Na+-dependent transporter, at 3,038,280 to 3,039,302 _2930 Ga0059261_2931: Ga0059261_2931 - Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family, at 3,039,328 to 3,039,861 _2931 Ga0059261_2932: Ga0059261_2932 - Serine/threonine protein kinase, at 3,039,971 to 3,042,688 _2932 Ga0059261_2933: Ga0059261_2933 - hypothetical protein, at 3,042,789 to 3,043,430 _2933 Ga0059261_2934: Ga0059261_2934 - hypothetical protein, at 3,043,420 to 3,043,806 _2934
Locus Name Description Strand Phenotype
Ga0059261_2924 Ga0059261_2924 Transposase and inactivated derivatives + no data
Ga0059261_2925 Ga0059261_2925 DNA replication protein + no data
Ga0059261_2926 Ga0059261_2926 Domain of unknown function (DUF4102) - insig.
Ga0059261_2927 Ga0059261_2927 hypothetical protein - no data
Ga0059261_2928 Ga0059261_2928 oxygen-dependent methionine synthase, putative oxygenase component MesX (from data) + strong
Ga0059261_2929 Ga0059261_2929 oxygen-dependent methionine synthase, methyltransferase component MesD (from data) + cofit
Ga0059261_2930 Ga0059261_2930 Predicted Na+-dependent transporter + strong
Ga0059261_2931 Ga0059261_2931 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family + insig.
Ga0059261_2932 Ga0059261_2932 Serine/threonine protein kinase - insig.
Ga0059261_2933 Ga0059261_2933 hypothetical protein + insig.
Ga0059261_2934 Ga0059261_2934 hypothetical protein + insig.

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