Gene info for Ga0059261_1941 in Sphingomonas koreensis DSMZ 15582

Updated annotation (from data): DNA damage response helicase, ligase-associated
Rationale: Conserved and specific phenotype: important for resisting cisplatin. Related to Lhr, which is either a DNA:DNA or DNA:RNA helicase, but lacks the long C-terminal extension that might have a regulatory role (see putative winged helix domain in E. coli lhr). This is also related to the archael protein saci_1500, which has also been linked to DNA damage response, as a mutant is sensitive to UV (PMID: 26148716)
Original annotation: DEXH box helicase, DNA ligase-associated
Type 1: Protein-coding gene
Located on scaffold Ga0059261_unitig_0_quiver.1, - strand, nucleotides 2,049,830 to 2,052,238
See nucleotide sequence around Ga0059261_1941 or for all of scaffold Ga0059261_unitig_0_quiver.1

Other databases: NCBI, uniprot: A0A2M8WCM4

Nearby Genes

500 ntGa0059261_1936 and Ga0059261_1937 are separated by 108 nucleotidesGa0059261_1937 and Ga0059261_1938 are separated by 150 nucleotidesGa0059261_1938 and Ga0059261_1939 are separated by 3 nucleotidesGa0059261_1939 and Ga0059261_1940 are separated by 31 nucleotidesGa0059261_1940 and Ga0059261_1941 are separated by 76 nucleotidesGa0059261_1941 and Ga0059261_1942 are separated by 63 nucleotidesGa0059261_1942 and Ga0059261_1943 overlap by 8 nucleotidesGa0059261_1943 and Ga0059261_1944 are separated by 155 nucleotidesGa0059261_1944 and Ga0059261_1945 are separated by 93 nucleotidesGa0059261_1945 and Ga0059261_1946 overlap by 4 nucleotides Ga0059261_1936: Ga0059261_1936 - transcriptional regulator, CarD family, at 2,045,886 to 2,046,419 _1936 Ga0059261_1937: Ga0059261_1937 - Protein of unknown function (DUF2807), at 2,046,528 to 2,047,253 _1937 Ga0059261_1938: Ga0059261_1938 - Protein of unknown function (DUF2807), at 2,047,404 to 2,048,105 _1938 Ga0059261_1939: Ga0059261_1939 - putative phosphoesterase, at 2,048,109 to 2,048,771 _1939 Ga0059261_1940: Ga0059261_1940 - Aspartyl protease, at 2,048,803 to 2,049,753 _1940 Ga0059261_1941: Ga0059261_1941 - DNA damage response helicase, ligase-associated (from data), at 2,049,830 to 2,052,238 _1941 Ga0059261_1942: Ga0059261_1942 - putative efflux pump, required for thallium (I) resistance (from data), at 2,052,302 to 2,052,631 _1942 Ga0059261_1943: Ga0059261_1943 - NAD-dependent protein deacetylases, SIR2 family, at 2,052,624 to 2,053,340 _1943 Ga0059261_1944: Ga0059261_1944 - GTP-binding protein Era, at 2,053,496 to 2,054,398 _1944 Ga0059261_1945: Ga0059261_1945 - Ketosteroid isomerase-related protein, at 2,054,492 to 2,054,926 _1945 Ga0059261_1946: Ga0059261_1946 - ribonuclease III, bacterial, at 2,054,923 to 2,055,588 _1946
Locus Name Description Strand Phenotype
Ga0059261_1936 Ga0059261_1936 transcriptional regulator, CarD family + no data
Ga0059261_1937 Ga0059261_1937 Protein of unknown function (DUF2807) + insig.
Ga0059261_1938 Ga0059261_1938 Protein of unknown function (DUF2807) + insig.
Ga0059261_1939 Ga0059261_1939 putative phosphoesterase - insig.
Ga0059261_1940 Ga0059261_1940 Aspartyl protease - insig.
Ga0059261_1941 Ga0059261_1941 DNA damage response helicase, ligase-associated (from data) - strong
Ga0059261_1942 Ga0059261_1942 putative efflux pump, required for thallium (I) resistance (from data) + strong
Ga0059261_1943 Ga0059261_1943 NAD-dependent protein deacetylases, SIR2 family + insig.
Ga0059261_1944 Ga0059261_1944 GTP-binding protein Era - no data
Ga0059261_1945 Ga0059261_1945 Ketosteroid isomerase-related protein + insig.
Ga0059261_1946 Ga0059261_1946 ribonuclease III, bacterial - no data

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