Gene info for PGA1_c03680 in Phaeobacter inhibens DSM 17395

Updated annotation (from data): (3S)-malyl-CoA thioesterase [EC:3.1.2.30]
Rationale: Specifically important for: L-Threonine; Potassium acetate. This is part of the ethylmalonyl-CoA cycle for acetate assimilation, and hence is important on threonine (cleaved to glycine and acetate via the PGA1_c34330 or kbl) and acetate (where it has a milder phenotype). The annotation of sit:TM1040_3520 has been updated to (3S)-malyl-CoA thioesterase [EC:3.1.2.30]. 69% similar to MCTE_RHOS4 (consistent with the KEGG annotation). SEED suggests that this is the malyl-CoA/methylmalyl-CoA lyase but that activity is probably provided by PGA1_c30490. (KEGG_correct)
Original annotation: putative citrate lyase subunit beta
Type 1: Protein-coding gene
Located on scaffold PGA1_c, + strand, nucleotides 355,129 to 355,983
See nucleotide sequence around PGA1_c03680 or for all of scaffold PGA1_c

Other databases: NCBI, IMG: 2510178933, uniprot: I7ETR9

Nearby Genes

500 ntPGA1_c03630 and PGA1_c03640 are separated by 337 nucleotidesPGA1_c03640 and PGA1_c03650 are separated by 104 nucleotidesPGA1_c03650 and PGA1_c03660 are separated by 163 nucleotidesPGA1_c03660 and PGA1_c03670 are separated by 109 nucleotidesPGA1_c03670 and PGA1_c03680 are separated by 383 nucleotidesPGA1_c03680 and PGA1_c03690 are separated by 35 nucleotidesPGA1_c03690 and PGA1_c03700 are separated by 6 nucleotidesPGA1_c03700 and PGA1_c03710 overlap by 1 nucleotidesPGA1_c03710 and PGA1_c03720 are separated by 23 nucleotidesPGA1_c03720 and PGA1_c03730 are separated by 32 nucleotides PGA1_c03630: PGA1_c03630 - succinyl-CoA ligase [ADP-forming] subunit beta, at 350,241 to 351,434 _c03630 PGA1_c03640: PGA1_c03640 - Predicted ATPase, at 351,772 to 352,320 _c03640 PGA1_c03650: PGA1_c03650 - malate dehydrogenase Mdh, at 352,425 to 353,387 _c03650 PGA1_c03660: PGA1_c03660 - Predicted permeases, at 353,551 to 354,306 _c03660 PGA1_c03670: PGA1_c03670 - hypothetical protein, at 354,416 to 354,745 _c03670 PGA1_c03680: PGA1_c03680 - (3S)-malyl-CoA thioesterase [EC:3.1.2.30] (from data), at 355,129 to 355,983 _c03680 PGA1_c03690: PGA1_c03690 - putative NnrU protein, at 356,019 to 356,567 _c03690 PGA1_c03700: PGA1_c03700 - Uncharacterized conserved small protein, at 356,574 to 356,777 _c03700 PGA1_c03710: PGA1_c03710 - Acyl dehydratase, at 356,777 to 357,808 _c03710 PGA1_c03720: PGA1_c03720 - phosphoglycerate mutase-like protein, at 357,832 to 358,461 _c03720 PGA1_c03730: PGA1_c03730 - Protein of unknown function (DUF1194)., at 358,494 to 359,183 _c03730
Locus Name Description Strand Phenotype
PGA1_c03630 PGA1_c03630 succinyl-CoA ligase [ADP-forming] subunit beta - no data
PGA1_c03640 PGA1_c03640 Predicted ATPase + insig.
PGA1_c03650 PGA1_c03650 malate dehydrogenase Mdh - no data
PGA1_c03660 PGA1_c03660 Predicted permeases + insig.
PGA1_c03670 PGA1_c03670 hypothetical protein - insig.
PGA1_c03680 PGA1_c03680 (3S)-malyl-CoA thioesterase [EC:3.1.2.30] (from data) + strong
PGA1_c03690 PGA1_c03690 putative NnrU protein + sig.
PGA1_c03700 PGA1_c03700 Uncharacterized conserved small protein + insig.
PGA1_c03710 PGA1_c03710 Acyl dehydratase + strong
PGA1_c03720 PGA1_c03720 phosphoglycerate mutase-like protein + insig.
PGA1_c03730 PGA1_c03730 Protein of unknown function (DUF1194). + insig.

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