Gene info for Psest_2438 in Pseudomonas stutzeri RCH2

Updated annotation (from data): 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
Rationale: Specifically important for utilizing L-Valine. Automated validation from mutant phenotype: the predicted function (3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN) was linked to the condition via a MetaCyc pathway. This annotation was also checked manually.
Original annotation: 3-hydroxyisobutyrate dehydrogenase
Type 1: Protein-coding gene
Located on scaffold Psest_Contig47.1, + strand, nucleotides 2,606,302 to 2,607,192
See nucleotide sequence around Psest_2438 or for all of scaffold Psest_Contig47.1

Other databases: NCBI, IMG: 2507212670, uniprot: L0GNL5

Nearby Genes

500 ntPsest_2433 and Psest_2434 are separated by 65 nucleotidesPsest_2434 and Psest_2435 are separated by 121 nucleotidesPsest_2435 and Psest_2436 are separated by 156 nucleotidesPsest_2436 and Psest_2437 are separated by 47 nucleotidesPsest_2437 and Psest_2438 are separated by 36 nucleotidesPsest_2438 and Psest_2439 are separated by 2 nucleotidesPsest_2439 and Psest_2440 are separated by 38 nucleotidesPsest_2440 and Psest_2441 are separated by 66 nucleotidesPsest_2441 and Psest_2442 are separated by 416 nucleotidesPsest_2442 and Psest_2443 are separated by 314 nucleotides Psest_2433: Psest_2433 - alpha-glucan phosphorylases, at 2,599,835 to 2,602,345 _2433 Psest_2434: Psest_2434 - Protein of unknown function (DUF2892)., at 2,602,411 to 2,602,764 _2434 Psest_2435: Psest_2435 - Transcriptional regulator, at 2,602,886 to 2,603,776 _2435 Psest_2436: Psest_2436 - Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) (from data), at 2,603,933 to 2,605,444 _2436 Psest_2437: Psest_2437 - Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) (from data), at 2,605,492 to 2,606,265 _2437 Psest_2438: Psest_2438 - 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data), at 2,606,302 to 2,607,192 _2438 Psest_2439: Psest_2439 - 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data), at 2,607,195 to 2,608,289 _2439 Psest_2440: Psest_2440 - isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data), at 2,608,328 to 2,609,479 _2440 Psest_2441: Psest_2441 - hypothetical protein, at 2,609,546 to 2,610,103 _2441 Psest_2442: Psest_2442 - hypothetical protein, at 2,610,520 to 2,610,648 _2442 Psest_2443: Psest_2443 - Predicted acyl-CoA transferases/carnitine dehydratase, at 2,610,963 to 2,612,045 _2443
Locus Name Description Strand Phenotype
Psest_2433 Psest_2433 alpha-glucan phosphorylases + insig.
Psest_2434 Psest_2434 Protein of unknown function (DUF2892). + insig.
Psest_2435 Psest_2435 Transcriptional regulator - sig.
Psest_2436 Psest_2436 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) (from data) + sig.
Psest_2437 Psest_2437 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) (from data) + strong
Psest_2438 Psest_2438 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) + sig.
Psest_2439 Psest_2439 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) + sig.
Psest_2440 Psest_2440 isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data) + sig.
Psest_2441 Psest_2441 hypothetical protein + strong
Psest_2442 Psest_2442 hypothetical protein + insig.
Psest_2443 Psest_2443 Predicted acyl-CoA transferases/carnitine dehydratase - insig.

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