Gene info for Psest_2436 in Pseudomonas stutzeri RCH2

Updated annotation (from data): Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
Rationale: Specifically important for utilizing L-Valine. Automated validation from mutant phenotype: the predicted function (RXN-11213) was linked to the condition via a MetaCyc pathway. This annotation was also checked manually.
Original annotation: methylmalonic acid semialdehyde dehydrogenase
Type 1: Protein-coding gene
Located on scaffold Psest_Contig47.1, + strand, nucleotides 2,603,933 to 2,605,444
See nucleotide sequence around Psest_2436 or for all of scaffold Psest_Contig47.1

Other databases: NCBI, IMG: 2507212668, uniprot: L0GJM3

Nearby Genes

500 ntPsest_2431 and Psest_2432 are separated by 182 nucleotidesPsest_2432 and Psest_2433 are separated by 77 nucleotidesPsest_2433 and Psest_2434 are separated by 65 nucleotidesPsest_2434 and Psest_2435 are separated by 121 nucleotidesPsest_2435 and Psest_2436 are separated by 156 nucleotidesPsest_2436 and Psest_2437 are separated by 47 nucleotidesPsest_2437 and Psest_2438 are separated by 36 nucleotidesPsest_2438 and Psest_2439 are separated by 2 nucleotidesPsest_2439 and Psest_2440 are separated by 38 nucleotidesPsest_2440 and Psest_2441 are separated by 66 nucleotides Psest_2431: Psest_2431 - Transglycosylase., at 2,595,358 to 2,598,477 _2431 Psest_2432: Psest_2432 - Uncharacterized protein conserved in bacteria, at 2,598,660 to 2,599,757 _2432 Psest_2433: Psest_2433 - alpha-glucan phosphorylases, at 2,599,835 to 2,602,345 _2433 Psest_2434: Psest_2434 - Protein of unknown function (DUF2892)., at 2,602,411 to 2,602,764 _2434 Psest_2435: Psest_2435 - Transcriptional regulator, at 2,602,886 to 2,603,776 _2435 Psest_2436: Psest_2436 - Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) (from data), at 2,603,933 to 2,605,444 _2436 Psest_2437: Psest_2437 - Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) (from data), at 2,605,492 to 2,606,265 _2437 Psest_2438: Psest_2438 - 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data), at 2,606,302 to 2,607,192 _2438 Psest_2439: Psest_2439 - 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data), at 2,607,195 to 2,608,289 _2439 Psest_2440: Psest_2440 - isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data), at 2,608,328 to 2,609,479 _2440 Psest_2441: Psest_2441 - hypothetical protein, at 2,609,546 to 2,610,103 _2441
Locus Name Description Strand Phenotype
Psest_2431 Psest_2431 Transglycosylase. + insig.
Psest_2432 Psest_2432 Uncharacterized protein conserved in bacteria + insig.
Psest_2433 Psest_2433 alpha-glucan phosphorylases + insig.
Psest_2434 Psest_2434 Protein of unknown function (DUF2892). + insig.
Psest_2435 Psest_2435 Transcriptional regulator - sig.
Psest_2436 Psest_2436 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) (from data) + sig.
Psest_2437 Psest_2437 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) (from data) + strong
Psest_2438 Psest_2438 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) + sig.
Psest_2439 Psest_2439 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) + sig.
Psest_2440 Psest_2440 isobutyryl-CoA dehydrogenase (EC 1.3.8.5) (from data) + sig.
Psest_2441 Psest_2441 hypothetical protein + strong

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