Gene info for PGA1_c17350 in Phaeobacter inhibens DSM 17395

Updated annotation (from data): 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
Rationale: Specifically important for utilizing L-Valine. Automated validation from mutant phenotype: the predicted function (3.1.2.4) was linked to the condition via a SEED subsystem. This annotation was also checked manually.
Original annotation: putative 3-hydroxyisobutyryl-CoA hydrolase
Type 1: Protein-coding gene
Located on scaffold PGA1_c, + strand, nucleotides 1,811,980 to 1,813,026
See nucleotide sequence around PGA1_c17350 or for all of scaffold PGA1_c

Other databases: NCBI, IMG: 2510180290, uniprot: I7EZN5

Nearby Genes

500 ntPGA1_c17300 and PGA1_c17310 are separated by 212 nucleotidesPGA1_c17310 and PGA1_c17320 are separated by 222 nucleotidesPGA1_c17320 and PGA1_c17330 are separated by 257 nucleotidesPGA1_c17330 and PGA1_c17340 are separated by 307 nucleotidesPGA1_c17340 and PGA1_c17350 are separated by 7 nucleotidesPGA1_c17350 and PGA1_c17360 overlap by 4 nucleotidesPGA1_c17360 and PGA1_c17370 are separated by 785 nucleotidesPGA1_c17370 and PGA1_c17380 are separated by 110 nucleotidesPGA1_c17380 and PGA1_c17390 are separated by 142 nucleotidesPGA1_c17390 and PGA1_c17400 are separated by 191 nucleotides PGA1_c17300: PGA1_c17300 - methylmalonate-semialdehyde dehydrogenase, at 1,804,942 to 1,806,441 _c17300 PGA1_c17310: PGA1_c17310 - putative fatty acid desaturase, at 1,806,654 to 1,807,682 _c17310 PGA1_c17320: PGA1_c17320 - Uncharacterized protein conserved in bacteria, at 1,807,905 to 1,808,504 _c17320 PGA1_c17330: PGA1_c17330 - Predicted O-linked N-acetylglucosamine transferase, SPINDLY family, at 1,808,762 to 1,810,519 _c17330 PGA1_c17340: PGA1_c17340 - acyl-CoA dehydrogenase AcdA, at 1,810,827 to 1,811,972 _c17340 PGA1_c17350: PGA1_c17350 - 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data), at 1,811,980 to 1,813,026 _c17350 PGA1_c17360: PGA1_c17360 - 3-hydroxyisobutyrate dehydrogenase MmsB, at 1,813,023 to 1,813,898 _c17360 PGA1_c17370: PGA1_c17370 - uvrABC system protein A, at 1,814,684 to 1,817,584 _c17370 PGA1_c17380: PGA1_c17380 - MFS type transporter, at 1,817,695 to 1,818,945 _c17380 PGA1_c17390: PGA1_c17390 - dihydrolipoyl dehydrogenase LpdA, at 1,819,088 to 1,820,482 _c17390 PGA1_c17400: PGA1_c17400 - Uncharacterized protein conserved in bacteria, at 1,820,674 to 1,821,252 _c17400
Locus Name Description Strand Phenotype
PGA1_c17300 PGA1_c17300 methylmalonate-semialdehyde dehydrogenase + strong
PGA1_c17310 PGA1_c17310 putative fatty acid desaturase + sig.
PGA1_c17320 PGA1_c17320 Uncharacterized protein conserved in bacteria + strong
PGA1_c17330 PGA1_c17330 Predicted O-linked N-acetylglucosamine transferase, SPINDLY family - insig.
PGA1_c17340 PGA1_c17340 acyl-CoA dehydrogenase AcdA + sig.
PGA1_c17350 PGA1_c17350 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) + strong
PGA1_c17360 PGA1_c17360 3-hydroxyisobutyrate dehydrogenase MmsB + insig.
PGA1_c17370 PGA1_c17370 uvrABC system protein A - strong
PGA1_c17380 PGA1_c17380 MFS type transporter - insig.
PGA1_c17390 PGA1_c17390 dihydrolipoyl dehydrogenase LpdA - no data
PGA1_c17400 PGA1_c17400 Uncharacterized protein conserved in bacteria - strong

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