Gene info for CCNA_01701 in Caulobacter crescentus NA1000

Updated annotation (from data): 3-keto-glycoside 1,2-lyase
Rationale: Important for the utilization of lactose, salicin, and raffinose. In a conserved cluster with the 3-ketoglycoside pathway starting with lacABC. Distantly related to BT2156, which is a 3-keto-beta-glycoside 1,2-lyase. Lactose and salicin are beta-glycosides but raffinose has two alpha linkages for its hexoses, which suggests that CCNA_01700 acts on alpha-glycosides as well. Note that another lyase (CCNA_01705) is also involved in lactose and raffinose utilization; the two enzymes may be partially redundant. CCNA_01701 has a signal peptide and is expected to be periplasmic
Original annotation: xylose isomerase family protein
Type 1: Protein-coding gene
Located on scaffold NC_011916, + strand, nucleotides 1,832,940 to 1,833,926
See nucleotide sequence around CCNA_01701 or for all of scaffold NC_011916

Other databases: NCBI, uniprot: A0A0H3C817

Nearby Genes

500 ntCCNA_01696 and CCNA_01697 are separated by 49 nucleotidesCCNA_01697 and CCNA_01698 are separated by 86 nucleotidesCCNA_01698 and CCNA_01699 overlap by 4 nucleotidesCCNA_01699 and CCNA_01700 are separated by 177 nucleotidesCCNA_01700 and CCNA_01701 are separated by 0 nucleotidesCCNA_01701 and CCNA_01702 overlap by 1 nucleotidesCCNA_01702 and CCNA_01703 overlap by 1 nucleotidesCCNA_01703 and CCNA_01704 are separated by 27 nucleotidesCCNA_01704 and CCNA_01705 are separated by 219 nucleotidesCCNA_01705 and CCNA_01706 are separated by 151 nucleotides CCNA_01696: CCNA_01696 - aminobenzoyl-glutamate transport protein, at 1,826,794 to 1,828,470 _01696 CCNA_01697: CCNA_01697 - putative poly-gamma-glutamate capsule biosynthesis protein, at 1,828,520 to 1,829,644 _01697 CCNA_01698: CCNA_01698 - 3-keto-glycoside 1,2-lyase (from data), at 1,829,731 to 1,830,516 _01698 CCNA_01699: CCNA_01699 - LacI-family transcriptional regulator, at 1,830,513 to 1,831,520 _01699 CCNA_01700: CCNA_01700 - 2-hydroxy-3-keto-glucal / 2-hydroxy-3-keto-galactal transporter (from data), at 1,831,698 to 1,832,939 _01700 CCNA_01701: CCNA_01701 - 3-keto-glycoside 1,2-lyase (from data), at 1,832,940 to 1,833,926 _01701 CCNA_01702: CCNA_01702 - 3-ketohexose reductase (NADH) (from data), at 1,833,926 to 1,835,056 _01702 CCNA_01703: CCNA_01703 - 3-ketohexose dehydratase (from data), at 1,835,056 to 1,836,111 _01703 CCNA_01704: CCNA_01704 - lacB: cytochrome c2 component of periplasmic glucoside 3-dehydrogenase (EC 1.1.99.13) (from data), at 1,836,139 to 1,836,501 _01704 CCNA_01705: CCNA_01705 - 3-keto-glycoside 1,2-lyase (from data), at 1,836,721 to 1,837,566 _01705 CCNA_01706: CCNA_01706 - lacA: subunit of periplasmic glucoside 3-dehydrogenase (EC 1.1.99.13) (from data), at 1,837,718 to 1,839,457 _01706
Locus Name Description Strand Phenotype
CCNA_01696 CCNA_01696 aminobenzoyl-glutamate transport protein - cofit
CCNA_01697 CCNA_01697 putative poly-gamma-glutamate capsule biosynthesis protein + sig.
CCNA_01698 CCNA_01698 3-keto-glycoside 1,2-lyase (from data) + strong
CCNA_01699 CCNA_01699 LacI-family transcriptional regulator - strong
CCNA_01700 CCNA_01700 2-hydroxy-3-keto-glucal / 2-hydroxy-3-keto-galactal transporter (from data) + strong
CCNA_01701 CCNA_01701 3-keto-glycoside 1,2-lyase (from data) + strong
CCNA_01702 CCNA_01702 3-ketohexose reductase (NADH) (from data) + strong
CCNA_01703 CCNA_01703 3-ketohexose dehydratase (from data) + strong
CCNA_01704 CCNA_01704 lacB: cytochrome c2 component of periplasmic glucoside 3-dehydrogenase (EC 1.1.99.13) (from data) + strong
CCNA_01705 CCNA_01705 3-keto-glycoside 1,2-lyase (from data) - strong
CCNA_01706 CCNA_01706 lacA: subunit of periplasmic glucoside 3-dehydrogenase (EC 1.1.99.13) (from data) + strong

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