Gene info for CA265_RS15855 in Pedobacter sp. GW460-11-11-14-LB5

Updated annotation (from data): 2-isopropylmalate synthase (EC 2.3.3.13)
Rationale: Important for fitness in defined media unless leucine is provided. 54% identical to 2-isopropylmalate synthase from Leptospira interrogans (Q8F445).
Original annotation: 2-isopropylmalate synthase
Type 1: Protein-coding gene
Located on scaffold NZ_CP021237, + strand, nucleotides 3,988,540 to 3,989,700
See nucleotide sequence around CA265_RS15855 or for all of scaffold NZ_CP021237

Other databases: NCBI, uniprot: A0A1X9Z750

Nearby Genes

500 ntCA265_RS15830 and CA265_RS15835 are separated by 32 nucleotidesCA265_RS15835 and CA265_RS15840 are separated by 80 nucleotidesCA265_RS15840 and CA265_RS15845 are separated by 84 nucleotidesCA265_RS15845 and CA265_RS15850 are separated by 4 nucleotidesCA265_RS15850 and CA265_RS15855 are separated by 10 nucleotidesCA265_RS15855 and CA265_RS15860 are separated by 270 nucleotidesCA265_RS15860 and CA265_RS15865 are separated by 211 nucleotidesCA265_RS15865 and CA265_RS15870 are separated by 216 nucleotidesCA265_RS15870 and CA265_RS15875 are separated by 135 nucleotidesCA265_RS15875 and CA265_RS15880 are separated by 8 nucleotides CA265_RS15830: CA265_RS15830 - 3-isopropylmalate dehydratase large subunit, at 3,983,428 to 3,984,840 _RS15830 CA265_RS15835: CA265_RS15835 - antibiotic biosynthesis monooxygenase, at 3,984,873 to 3,985,217 _RS15835 CA265_RS15840: CA265_RS15840 - 3-isopropylmalate dehydratase small subunit, at 3,985,298 to 3,985,885 _RS15840 CA265_RS15845: CA265_RS15845 - molybdenum ABC transporter ATP-binding protein, at 3,985,970 to 3,987,433 _RS15845 CA265_RS15850: CA265_RS15850 - 3-isopropylmalate dehydrogenase, at 3,987,438 to 3,988,529 _RS15850 CA265_RS15855: CA265_RS15855 - 2-isopropylmalate synthase (EC 2.3.3.13) (from data), at 3,988,540 to 3,989,700 _RS15855 CA265_RS15860: CA265_RS15860 - threonine deaminase (EC 4.3.1.19) (from data), at 3,989,971 to 3,991,221 _RS15860 CA265_RS15865: CA265_RS15865 - cupin, at 3,991,433 to 3,991,783 _RS15865 CA265_RS15870: CA265_RS15870 - hypothetical protein, at 3,992,000 to 3,992,560 _RS15870 CA265_RS15875: CA265_RS15875 - hypothetical protein, at 3,992,696 to 3,993,106 _RS15875 CA265_RS15880: CA265_RS15880 - sugar ABC transporter ATP-binding protein, at 3,993,115 to 3,994,107 _RS15880
Locus Name Description Strand Phenotype
CA265_RS15830 CA265_RS15830 3-isopropylmalate dehydratase large subunit + strong
CA265_RS15835 CA265_RS15835 antibiotic biosynthesis monooxygenase + strong
CA265_RS15840 CA265_RS15840 3-isopropylmalate dehydratase small subunit + strong
CA265_RS15845 CA265_RS15845 molybdenum ABC transporter ATP-binding protein + strong
CA265_RS15850 CA265_RS15850 3-isopropylmalate dehydrogenase + strong
CA265_RS15855 CA265_RS15855 2-isopropylmalate synthase (EC 2.3.3.13) (from data) + strong
CA265_RS15860 CA265_RS15860 threonine deaminase (EC 4.3.1.19) (from data) + strong
CA265_RS15865 CA265_RS15865 cupin + insig.
CA265_RS15870 CA265_RS15870 hypothetical protein - insig.
CA265_RS15875 CA265_RS15875 hypothetical protein + insig.
CA265_RS15880 CA265_RS15880 sugar ABC transporter ATP-binding protein - strong

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