Gene info for BWI76_RS10795 in Klebsiella michiganensis M5al

Updated annotation (from data): L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2)
Rationale: Specifically important for utilizing L-Proline. Automated validation from mutant phenotype: the predicted function (1.2.1.88, 1.5.5.2) was linked to the condition via a SEED subsystem. This annotation was also checked manually.
Original annotation: trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase
Type 1: Protein-coding gene
Located on scaffold NZ_CP020657, - strand, nucleotides 2,277,440 to 2,281,402
See nucleotide sequence around BWI76_RS10795 or for all of scaffold NZ_CP020657

Other databases: NCBI, uniprot: A0A285B255

Nearby Genes

500 ntBWI76_RS10770 and BWI76_RS10775 overlap by 8 nucleotidesBWI76_RS10775 and BWI76_RS10780 overlap by 1 nucleotidesBWI76_RS10780 and BWI76_RS10785 are separated by 286 nucleotidesBWI76_RS10785 and BWI76_RS10790 overlap by 4 nucleotidesBWI76_RS10790 and BWI76_RS10795 are separated by 193 nucleotidesBWI76_RS10795 and BWI76_RS10800 are separated by 427 nucleotidesBWI76_RS10800 and BWI76_RS10805 are separated by 112 nucleotidesBWI76_RS10805 and BWI76_RS10810 are separated by 69 nucleotidesBWI76_RS10810 and BWI76_RS10815 are separated by 273 nucleotidesBWI76_RS10815 and BWI76_RS10820 are separated by 52 nucleotides BWI76_RS10770: BWI76_RS10770 - pyrimidine utilization protein C, at 2,273,743 to 2,274,135 _RS10770 BWI76_RS10775: BWI76_RS10775 - pyrimidine utilization protein B, at 2,274,128 to 2,274,838 _RS10775 BWI76_RS10780: BWI76_RS10780 - pyrimidine utilization protein A, at 2,274,838 to 2,275,929 _RS10780 BWI76_RS10785: BWI76_RS10785 - transcriptional regulator, at 2,276,216 to 2,276,854 _RS10785 BWI76_RS10790: BWI76_RS10790 - hypothetical protein, at 2,276,851 to 2,277,246 _RS10790 BWI76_RS10795: BWI76_RS10795 - L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data), at 2,277,440 to 2,281,402 _RS10795 BWI76_RS10800: BWI76_RS10800 - sodium:proline symporter, at 2,281,830 to 2,283,338 _RS10800 BWI76_RS10805: BWI76_RS10805 - hypothetical protein, at 2,283,451 to 2,283,885 _RS10805 BWI76_RS10810: BWI76_RS10810 - NupC family nucleoside transporter, at 2,283,955 to 2,285,139 _RS10810 BWI76_RS10815: BWI76_RS10815 - iron permease, at 2,285,413 to 2,286,243 _RS10815 BWI76_RS10820: BWI76_RS10820 - iron uptake system protein EfeO, at 2,286,296 to 2,287,423 _RS10820
Locus Name Description Strand Phenotype
BWI76_RS10770 BWI76_RS10770 pyrimidine utilization protein C - sig.
BWI76_RS10775 BWI76_RS10775 pyrimidine utilization protein B - strong
BWI76_RS10780 BWI76_RS10780 pyrimidine utilization protein A - cofit
BWI76_RS10785 BWI76_RS10785 transcriptional regulator + strong
BWI76_RS10790 BWI76_RS10790 hypothetical protein - insig.
BWI76_RS10795 BWI76_RS10795 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) - strong
BWI76_RS10800 BWI76_RS10800 sodium:proline symporter + insig.
BWI76_RS10805 BWI76_RS10805 hypothetical protein + insig.
BWI76_RS10810 BWI76_RS10810 NupC family nucleoside transporter - insig.
BWI76_RS10815 BWI76_RS10815 iron permease + sig.
BWI76_RS10820 BWI76_RS10820 iron uptake system protein EfeO + sig.

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