Gene info for BWI76_RS08725 in Klebsiella michiganensis M5al

Updated annotation (from data): Formiminoglutamase (EC 3.5.3.8)
Rationale: Specifically important for utilizing L-Histidine. Automated validation from mutant phenotype: the predicted function (FORMIMINOGLUTAMASE-RXN) was linked to the condition via a MetaCyc pathway. This annotation was also checked manually.
Original annotation: formimidoylglutamase
Type 1: Protein-coding gene
Located on scaffold NZ_CP020657, + strand, nucleotides 1,837,820 to 1,838,776
See nucleotide sequence around BWI76_RS08725 or for all of scaffold NZ_CP020657

Other databases: NCBI, uniprot: A0A285B136

Nearby Genes

500 ntBWI76_RS08700 and BWI76_RS08705 are separated by 94 nucleotidesBWI76_RS08705 and BWI76_RS08710 are separated by 58 nucleotidesBWI76_RS08710 and BWI76_RS08715 are separated by 415 nucleotidesBWI76_RS08715 and BWI76_RS08720 are separated by 230 nucleotidesBWI76_RS08720 and BWI76_RS08725 overlap by 4 nucleotidesBWI76_RS08725 and BWI76_RS08730 are separated by 53 nucleotidesBWI76_RS08730 and BWI76_RS08735 are separated by 143 nucleotidesBWI76_RS08735 and BWI76_RS08740 overlap by 4 nucleotidesBWI76_RS08740 and BWI76_RS08745 are separated by 100 nucleotidesBWI76_RS08745 and BWI76_RS08750 are separated by 104 nucleotides BWI76_RS08700: BWI76_RS08700 - helix-turn-helix-type transcriptional regulator, at 1,833,019 to 1,833,750 _RS08700 BWI76_RS08705: BWI76_RS08705 - putative LuxR family regulatory protein, at 1,833,845 to 1,834,399 _RS08705 BWI76_RS08710: BWI76_RS08710 - hypothetical protein, at 1,834,458 to 1,834,676 _RS08710 BWI76_RS08715: BWI76_RS08715 - acyl-CoA thioesterase, at 1,835,092 to 1,836,375 _RS08715 BWI76_RS08720: BWI76_RS08720 - imidazolonepropionase, at 1,836,606 to 1,837,823 _RS08720 BWI76_RS08725: BWI76_RS08725 - Formiminoglutamase (EC 3.5.3.8) (from data), at 1,837,820 to 1,838,776 _RS08725 BWI76_RS08730: BWI76_RS08730 - histidine utilization repressor, at 1,838,830 to 1,839,555 _RS08730 BWI76_RS08735: BWI76_RS08735 - Urocanate hydratase (EC 4.2.1.49) (from data), at 1,839,699 to 1,841,387 _RS08735 BWI76_RS08740: BWI76_RS08740 - Histidine ammonia-lyase (EC 4.3.1.3) (from data), at 1,841,384 to 1,842,907 _RS08740 BWI76_RS08745: BWI76_RS08745 - proline-specific permease, at 1,843,008 to 1,844,387 _RS08745 BWI76_RS08750: BWI76_RS08750 - kinase inhibitor, at 1,844,492 to 1,844,968 _RS08750
Locus Name Description Strand Phenotype
BWI76_RS08700 BWI76_RS08700 helix-turn-helix-type transcriptional regulator + sig.
BWI76_RS08705 BWI76_RS08705 putative LuxR family regulatory protein - insig.
BWI76_RS08710 BWI76_RS08710 hypothetical protein - insig.
BWI76_RS08715 BWI76_RS08715 acyl-CoA thioesterase - sig.
BWI76_RS08720 BWI76_RS08720 imidazolonepropionase + insig.
BWI76_RS08725 BWI76_RS08725 Formiminoglutamase (EC 3.5.3.8) (from data) + strong
BWI76_RS08730 BWI76_RS08730 histidine utilization repressor + strong
BWI76_RS08735 BWI76_RS08735 Urocanate hydratase (EC 4.2.1.49) (from data) + strong
BWI76_RS08740 BWI76_RS08740 Histidine ammonia-lyase (EC 4.3.1.3) (from data) + strong
BWI76_RS08745 BWI76_RS08745 proline-specific permease + insig.
BWI76_RS08750 BWI76_RS08750 kinase inhibitor - insig.

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