Gene info for BWI76_RS01745 in Klebsiella michiganensis M5al

Updated annotation (from data): Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140)
Rationale: Specifically important for utilizing L-Sorbose. Automated validation from mutant phenotype: the predicted function (1.1.1.140) was linked to the condition via a SEED subsystem. This annotation was also checked manually.
Original annotation: sorbitol-6-phosphate 2-dehydrogenase
Type 1: Protein-coding gene
Located on scaffold NZ_CP020657, - strand, nucleotides 356,593 to 357,396
See nucleotide sequence around BWI76_RS01745 or for all of scaffold NZ_CP020657

Other databases: NCBI, uniprot: A0A285AW98

Nearby Genes

500 ntBWI76_RS01720 and BWI76_RS01725 are separated by 123 nucleotidesBWI76_RS01725 and BWI76_RS01730 are separated by 11 nucleotidesBWI76_RS01730 and BWI76_RS01735 are separated by 188 nucleotidesBWI76_RS01735 and BWI76_RS01740 overlap by 1 nucleotidesBWI76_RS01740 and BWI76_RS01745 are separated by 9 nucleotidesBWI76_RS01745 and BWI76_RS01750 are separated by 70 nucleotidesBWI76_RS01750 and BWI76_RS01755 are separated by 348 nucleotidesBWI76_RS01755 and BWI76_RS01760 overlap by 4 nucleotidesBWI76_RS01760 and BWI76_RS01765 are separated by 185 nucleotidesBWI76_RS01765 and BWI76_RS01770 are separated by 111 nucleotides BWI76_RS01720: BWI76_RS01720 - L-sorbose 1-phosphate reductase (EC 1.1.1.-) (from data), at 352,507 to 353,736 _RS01720 BWI76_RS01725: BWI76_RS01725 - PTS mannose/fructose/sorbose family transporter subunit IID, at 353,860 to 354,684 _RS01725 BWI76_RS01730: BWI76_RS01730 - PTS mannose/fructose/sorbose transporter subunit IIC, at 354,696 to 355,493 _RS01730 BWI76_RS01735: BWI76_RS01735 - PTS mannose/fructose/sorbose family transporter subunit IIB, at 355,682 to 356,176 _RS01735 BWI76_RS01740: BWI76_RS01740 - PTS enzyme IIAB, mannose-specific, at 356,176 to 356,583 _RS01740 BWI76_RS01745: BWI76_RS01745 - Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) (from data), at 356,593 to 357,396 _RS01745 BWI76_RS01750: BWI76_RS01750 - Cro/Cl family transcriptional regulator, at 357,467 to 358,414 _RS01750 BWI76_RS01755: BWI76_RS01755 - 23S rRNA pseudouridine synthase F, at 358,763 to 359,635 _RS01755 BWI76_RS01760: BWI76_RS01760 - hypothetical protein, at 359,632 to 359,904 _RS01760 BWI76_RS01765: BWI76_RS01765 - hypothetical protein, at 360,090 to 361,031 _RS01765 BWI76_RS01770: BWI76_RS01770 - transcriptional regulatory protein RtcR, at 361,143 to 362,723 _RS01770
Locus Name Description Strand Phenotype
BWI76_RS01720 BWI76_RS01720 L-sorbose 1-phosphate reductase (EC 1.1.1.-) (from data) - strong
BWI76_RS01725 BWI76_RS01725 PTS mannose/fructose/sorbose family transporter subunit IID - strong
BWI76_RS01730 BWI76_RS01730 PTS mannose/fructose/sorbose transporter subunit IIC - strong
BWI76_RS01735 BWI76_RS01735 PTS mannose/fructose/sorbose family transporter subunit IIB - strong
BWI76_RS01740 BWI76_RS01740 PTS enzyme IIAB, mannose-specific - strong
BWI76_RS01745 BWI76_RS01745 Sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) (from data) - strong
BWI76_RS01750 BWI76_RS01750 Cro/Cl family transcriptional regulator - strong
BWI76_RS01755 BWI76_RS01755 23S rRNA pseudouridine synthase F + insig.
BWI76_RS01760 BWI76_RS01760 hypothetical protein - no data
BWI76_RS01765 BWI76_RS01765 hypothetical protein - insig.
BWI76_RS01770 BWI76_RS01770 transcriptional regulatory protein RtcR - insig.

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