Gene info for BPHYT_RS16120 in Burkholderia phytofirmans PsJN

Updated annotation (from data): sorbitol dehydrogenase, D-fructose forming (EC 1.1.1.14)
Rationale: Specifically important for: D-Sorbitol. The KEGG EC number implies that sorbose would be the product, but it is not clear how sorbose would be consumed. The only other genes with specific phenotypes on sorbitol are an ABC transporter, the fructokinase BPHYT_RS02045, and an apparent polar effect on mannose isomerase BPHYT_RS02050. Also this protein is 60% similar to DHSO_RHOSH (polS), which is annotated in UniProt as forming sorbose but is believed to form D-fructose, see PMID: 15805591 (SEED_correct)
Original annotation: sorbitol dehydrogenase
Type 1: Protein-coding gene
Located on scaffold NC_010681, - strand, nucleotides 3,657,289 to 3,658,071
See nucleotide sequence around BPHYT_RS16120 or for all of scaffold NC_010681

Other databases: NCBI, uniprot: B2SYA3

Nearby Genes

500 ntBPHYT_RS16095 and BPHYT_RS16100 are separated by 106 nucleotidesBPHYT_RS16100 and BPHYT_RS16105 overlap by 4 nucleotidesBPHYT_RS16105 and BPHYT_RS16110 overlap by 4 nucleotidesBPHYT_RS16110 and BPHYT_RS16115 are separated by 152 nucleotidesBPHYT_RS16115 and BPHYT_RS16120 are separated by 72 nucleotidesBPHYT_RS16120 and BPHYT_RS16125 are separated by 332 nucleotidesBPHYT_RS16125 and BPHYT_RS16130 are separated by 59 nucleotidesBPHYT_RS16130 and BPHYT_RS16135 overlap by 4 nucleotidesBPHYT_RS16135 and BPHYT_RS16140 overlap by 8 nucleotidesBPHYT_RS16140 and BPHYT_RS16145 are separated by 58 nucleotides BPHYT_RS16095: BPHYT_RS16095 - ABC transporter for D-Sorbitol, ATPase component (from data), at 3,652,008 to 3,653,117 _RS16095 BPHYT_RS16100: BPHYT_RS16100 - HAD family hydrolase, at 3,653,224 to 3,653,937 _RS16100 BPHYT_RS16105: BPHYT_RS16105 - ABC transporter for D-Sorbitol, permease component 1 (from data), at 3,653,934 to 3,654,809 _RS16105 BPHYT_RS16110: BPHYT_RS16110 - ABC transporter for D-Sorbitol, permease component 2 (from data), at 3,654,806 to 3,655,741 _RS16110 BPHYT_RS16115: BPHYT_RS16115 - ABC transporter for D-Sorbitol, periplasmic substrate-binding component (from data), at 3,655,894 to 3,657,216 _RS16115 BPHYT_RS16120: BPHYT_RS16120 - sorbitol dehydrogenase, D-fructose forming (EC 1.1.1.14) (from data), at 3,657,289 to 3,658,071 _RS16120 BPHYT_RS16125: BPHYT_RS16125 - Fur family transcriptional regulator, at 3,658,404 to 3,658,898 _RS16125 BPHYT_RS16130: BPHYT_RS16130 - cation ABC transporter substrate-binding protein, at 3,658,958 to 3,659,926 _RS16130 BPHYT_RS16135: BPHYT_RS16135 - ABC transporter ATP-binding protein, at 3,659,923 to 3,660,864 _RS16135 BPHYT_RS16140: BPHYT_RS16140 - ABC transporter permease, at 3,660,857 to 3,661,639 _RS16140 BPHYT_RS16145: BPHYT_RS16145 - S-formylglutathione hydrolase, at 3,661,698 to 3,662,549 _RS16145
Locus Name Description Strand Phenotype
BPHYT_RS16095 BPHYT_RS16095 ABC transporter for D-Sorbitol, ATPase component (from data) - strong
BPHYT_RS16100 BPHYT_RS16100 HAD family hydrolase - no data
BPHYT_RS16105 BPHYT_RS16105 ABC transporter for D-Sorbitol, permease component 1 (from data) - strong
BPHYT_RS16110 BPHYT_RS16110 ABC transporter for D-Sorbitol, permease component 2 (from data) - strong
BPHYT_RS16115 BPHYT_RS16115 ABC transporter for D-Sorbitol, periplasmic substrate-binding component (from data) - strong
BPHYT_RS16120 BPHYT_RS16120 sorbitol dehydrogenase, D-fructose forming (EC 1.1.1.14) (from data) - strong
BPHYT_RS16125 BPHYT_RS16125 Fur family transcriptional regulator + insig.
BPHYT_RS16130 BPHYT_RS16130 cation ABC transporter substrate-binding protein + strong
BPHYT_RS16135 BPHYT_RS16135 ABC transporter ATP-binding protein + strong
BPHYT_RS16140 BPHYT_RS16140 ABC transporter permease + no data
BPHYT_RS16145 BPHYT_RS16145 S-formylglutathione hydrolase - insig.

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