Gene info for BBR_RS19535 in Bifidobacterium breve UCC2003

Updated annotation (from data): homoserine kinase (EC 2.7.1.39)
Rationale: Important for fitness in minimal media and cofit with the threonine synthase (BBR_RS14070), the succeeding step in threonine synthesis. Another potential candidate for this enzyme is BBR_RS19535, but that protein is fused to AroB and must be shikimate kinase
Original annotation: homoserine kinase
Type 1: Protein-coding gene
Located on scaffold NC_020517, - strand, nucleotides 2,166,352 to 2,167,464
See nucleotide sequence around BBR_RS19535 or for all of scaffold NC_020517

Other databases: NCBI

Nearby Genes

500 ntBBR_RS19510 and BBR_RS19515 overlap by 4 nucleotidesBBR_RS19515 and BBR_RS19520 are separated by 331 nucleotidesBBR_RS19520 and BBR_RS19525 overlap by 10 nucleotidesBBR_RS19525 and BBR_RS19530 are separated by 62 nucleotidesBBR_RS19530 and BBR_RS19535 are separated by 137 nucleotidesBBR_RS19535 and BBR_RS19540 are separated by 94 nucleotidesBBR_RS19540 and BBR_RS19545 are separated by 193 nucleotidesBBR_RS19545 and BBR_RS19550 overlap by 4 nucleotidesBBR_RS19550 and BBR_RS19555 are separated by 95 nucleotidesBBR_RS19555 and BBR_RS19560 are separated by 2 nucleotides BBR_RS19510: BBR_RS19510 - ABC transporter permease, at 2,161,294 to 2,162,742 _RS19510 BBR_RS19515: BBR_RS19515 - ABC transporter ATP-binding protein, at 2,162,739 to 2,163,599 _RS19515 BBR_RS19520: BBR_RS19520 - DUF1778 domain-containing protein, at 2,163,931 to 2,164,200 _RS19520 BBR_RS19525: BBR_RS19525 - N-acetyltransferase, at 2,164,191 to 2,164,700 _RS19525 BBR_RS19530: BBR_RS19530 - septum formation protein Maf, at 2,164,763 to 2,166,214 _RS19530 BBR_RS19535: BBR_RS19535 - homoserine kinase (EC 2.7.1.39) (from data), at 2,166,352 to 2,167,464 _RS19535 BBR_RS19540: BBR_RS19540 - homoserine dehydrogenase, at 2,167,559 to 2,168,875 _RS19540 BBR_RS19545: BBR_RS19545 - PTS glucose-like IIB component, at 2,169,069 to 2,169,563 _RS19545 BBR_RS19550: BBR_RS19550 - PTS N-acetylglucosamine transporter subunit IIABC, at 2,169,560 to 2,170,063 _RS19550 BBR_RS19555: BBR_RS19555 - diaminopimelate decarboxylase (EC 4.1.1.20) (from data), at 2,170,159 to 2,171,781 _RS19555 BBR_RS19560: BBR_RS19560 - arginine--tRNA ligase, at 2,171,784 to 2,173,646 _RS19560
Locus Name Description Strand Phenotype
BBR_RS19510 BBR_RS19510 ABC transporter permease - insig.
BBR_RS19515 BBR_RS19515 ABC transporter ATP-binding protein - sig.
BBR_RS19520 BBR_RS19520 DUF1778 domain-containing protein + insig.
BBR_RS19525 BBR_RS19525 N-acetyltransferase + cofit
BBR_RS19530 BBR_RS19530 septum formation protein Maf - insig.
BBR_RS19535 BBR_RS19535 homoserine kinase (EC 2.7.1.39) (from data) - strong
BBR_RS19540 BBR_RS19540 homoserine dehydrogenase - strong
BBR_RS19545 BBR_RS19545 PTS glucose-like IIB component + insig.
BBR_RS19550 BBR_RS19550 PTS N-acetylglucosamine transporter subunit IIABC + insig.
BBR_RS19555 BBR_RS19555 diaminopimelate decarboxylase (EC 4.1.1.20) (from data) - strong
BBR_RS19560 BBR_RS19560 arginine--tRNA ligase - no data

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