Gene info for BBR_RS12915 in Bifidobacterium breve UCC2003

Updated annotation (from data): glycine synthesis protein GlyXS
Rationale: Important when glycine is not available. A homolog from Methanococcus has similar phenotypes, so this appears to be part of a novel route to glycine, along with GlyXS (BBR_RS12920). Also has milder phenotypes on Irgasan and Clotrimazole which are not explained.
Original annotation: ACT domain-containing protein
Type 1: Protein-coding gene
Located on scaffold NC_020517, + strand, nucleotides 650,485 to 650,757
See nucleotide sequence around BBR_RS12915 or for all of scaffold NC_020517

Other databases: NCBI

Nearby Genes

500 ntBBR_RS12895 and BBR_RS12900 are separated by 305 nucleotidesBBR_RS12900 and BBR_RS12905 are separated by 5 nucleotidesBBR_RS12905 and BBR_RS12910 are separated by 17 nucleotidesBBR_RS12910 and BBR_RS20735 are separated by 411 nucleotidesBBR_RS20735 and BBR_RS12915 are separated by 72 nucleotidesBBR_RS12915 and BBR_RS12920 are separated by 141 nucleotidesBBR_RS12920 and BBR_RS12925 are separated by 181 nucleotidesBBR_RS12925 and BBR_RS12930 are separated by 273 nucleotidesBBR_RS12930 and BBR_RS12935 are separated by 20 nucleotidesBBR_RS12935 and BBR_RS12940 are separated by 400 nucleotides BBR_RS12895: BBR_RS12895 - quinone-dependent dihydroorotate dehydrogenase, at 644,932 to 646,083 _RS12895 BBR_RS12900: BBR_RS12900 - DeoR/GlpR transcriptional regulator, at 646,389 to 647,192 _RS12900 BBR_RS12905: BBR_RS12905 - galactose-1-phosphate uridylyltransferase, at 647,198 to 648,448 _RS12905 BBR_RS12910: BBR_RS12910 - galactokinase, at 648,466 to 649,716 _RS12910 BBR_RS20735: BBR_RS20735 - hypothetical protein, at 650,128 to 650,412 _RS20735 BBR_RS12915: BBR_RS12915 - glycine synthesis protein GlyXS (from data), at 650,485 to 650,757 _RS12915 BBR_RS12920: BBR_RS12920 - glycine synthesis protein GlyXL (from data), at 650,899 to 652,263 _RS12920 BBR_RS12925: BBR_RS12925 - hypothetical protein, at 652,445 to 652,648 _RS12925 BBR_RS12930: BBR_RS12930 - tRNA (cytidine(34)-2'-O)-methyltransferase, at 652,922 to 653,584 _RS12930 BBR_RS12935: BBR_RS12935 - A/G-specific adenine glycosylase, at 653,605 to 654,567 _RS12935 BBR_RS12940: BBR_RS12940 - hypothetical protein, at 654,968 to 655,549 _RS12940
Locus Name Description Strand Phenotype
BBR_RS12895 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase - strong
BBR_RS12900 BBR_RS12900 DeoR/GlpR transcriptional regulator + cofit
BBR_RS12905 BBR_RS12905 galactose-1-phosphate uridylyltransferase + strong
BBR_RS12910 BBR_RS12910 galactokinase + strong
BBR_RS20735 BBR_RS20735 hypothetical protein + insig.
BBR_RS12915 BBR_RS12915 glycine synthesis protein GlyXS (from data) + sig.
BBR_RS12920 BBR_RS12920 glycine synthesis protein GlyXL (from data) + strong
BBR_RS12925 BBR_RS12925 hypothetical protein + insig.
BBR_RS12930 BBR_RS12930 tRNA (cytidine(34)-2'-O)-methyltransferase - insig.
BBR_RS12935 BBR_RS12935 A/G-specific adenine glycosylase + insig.
BBR_RS12940 BBR_RS12940 hypothetical protein + strong

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