Gene info for Ac3H11_612 in Acidovorax sp. GW101-3H11

Updated annotation (from data): 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26)
Rationale: Specifically important for utilizing L-Arabinose. Automated validation from mutant phenotype: the predicted function (25-DIOXOVALERATE-DEHYDROGENASE-RXN) was linked to the condition via a MetaCyc pathway. This annotation was also checked manually.
Original annotation: 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26)
Type 1: Protein-coding gene
Located on scaffold scaffold5/37, - strand, nucleotides 50,272 to 51,723
See nucleotide sequence around Ac3H11_612 or for all of scaffold scaffold5/37

Other databases: uniprot: A0A165IRT0

Nearby Genes

500 ntAc3H11_607 and Ac3H11_608 overlap by 4 nucleotidesAc3H11_608 and Ac3H11_609 are separated by 1 nucleotidesAc3H11_609 and Ac3H11_610 are separated by 110 nucleotidesAc3H11_610 and Ac3H11_611 are separated by 214 nucleotidesAc3H11_611 and Ac3H11_612 are separated by 70 nucleotidesAc3H11_612 and Ac3H11_613 are separated by 144 nucleotidesAc3H11_613 and Ac3H11_614 are separated by 1146 nucleotidesAc3H11_614 and Ac3H11_615 are separated by 99 nucleotidesAc3H11_615 and Ac3H11_616 are separated by 191 nucleotidesAc3H11_616 and Ac3H11_617 are separated by 72 nucleotides Ac3H11_607 - Predicted L-arabinose ABC transport system, ATP-binding protein, at 43,539 to 45,092 _607 Ac3H11_608 - L-arabinose transport system permease protein (TC 3.A.1.2.2), at 45,089 to 46,318 _608 Ac3H11_609 - L-arabinose transport ATP-binding protein AraG (TC 3.A.1.2.2), at 46,320 to 47,837 _609 Ac3H11_610 - L-arabinose-binding periplasmic protein precursor AraF (TC 3.A.1.2.2), at 47,948 to 49,018 _610 Ac3H11_611 - Putative sugar ABC transport system, periplasmic binding protein YtfQ precursor, at 49,233 to 50,201 _611 Ac3H11_612 - 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) (from data), at 50,272 to 51,723 _612 Ac3H11_613 - Galactose-binding protein regulator, at 51,868 to 52,830 _613 Ac3H11_614 - L-arabinose 1-dehydrogenase; D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data), at 53,977 to 54,819 _614 Ac3H11_615 - L-arabinolactonase/D-galactonolactonase (EC 3.1.1.15; EC 3.1.1.25) (from data), at 54,919 to 55,869 _615 Ac3H11_616 - Aldose 1-epimerase, at 56,061 to 57,002 _616 Ac3H11_617 - hypothetical protein, at 57,075 to 57,923 _617
Locus Name Description Strand Phenotype
Ac3H11_607 Predicted L-arabinose ABC transport system, ATP-binding protein - strong
Ac3H11_608 L-arabinose transport system permease protein (TC 3.A.1.2.2) - strong
Ac3H11_609 L-arabinose transport ATP-binding protein AraG (TC 3.A.1.2.2) - strong
Ac3H11_610 L-arabinose-binding periplasmic protein precursor AraF (TC 3.A.1.2.2) - strong
Ac3H11_611 Putative sugar ABC transport system, periplasmic binding protein YtfQ precursor - sig.
Ac3H11_612 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) (from data) - strong
Ac3H11_613 Galactose-binding protein regulator + strong
Ac3H11_614 L-arabinose 1-dehydrogenase; D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) - strong
Ac3H11_615 L-arabinolactonase/D-galactonolactonase (EC 3.1.1.15; EC 3.1.1.25) (from data) + strong
Ac3H11_616 Aldose 1-epimerase + sig.
Ac3H11_617 hypothetical protein - insig.

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