Gene info for AO353_26580 in Pseudomonas fluorescens FW300-N2E3

Updated annotation (from data): Dihydropyrimidine dehydrogenase (NADP(+)) (EC 1.3.1.2)
Rationale: Specifically important for utilizing Uridine. Automated validation from mutant phenotype: the predicted function (1.3.1.2) was linked to the condition via a SEED subsystem. This annotation was also checked manually.
Original annotation: dihydropyrimidine dehydrogenase
Type 1: Protein-coding gene
Located on scaffold CP012830, + strand, nucleotides 5,820,950 to 5,822,224
See nucleotide sequence around AO353_26580 or for all of scaffold CP012830

Other databases: NCBI, uniprot: A0A0N9WQW9

Nearby Genes

500 ntAO353_26555 and AO353_26560 are separated by 263 nucleotidesAO353_26560 and AO353_26565 are separated by 129 nucleotidesAO353_26565 and AO353_26570 are separated by 622 nucleotidesAO353_26570 and AO353_26575 are separated by 230 nucleotidesAO353_26575 and AO353_26580 are separated by 0 nucleotidesAO353_26580 and AO353_26585 are separated by 122 nucleotidesAO353_26585 and AO353_26590 are separated by 125 nucleotidesAO353_26590 and AO353_26595 are separated by 3 nucleotidesAO353_26595 and AO353_26600 are separated by 30 nucleotidesAO353_26600 and AO353_26605 overlap by 4 nucleotides AO353_26555: AO353_26555 - DHH family protein, at 5,813,211 to 5,814,125 _26555 AO353_26560: AO353_26560 - Beta-ureidopropionase (EC 3.5.1.6) (from data), at 5,814,389 to 5,815,672 _26560 AO353_26565: AO353_26565 - nitrate reductase, at 5,815,802 to 5,817,289 _26565 AO353_26570: AO353_26570 - Dihydropyrimidinase (EC 3.5.2.2) (from data), at 5,817,912 to 5,819,351 _26570 AO353_26575: AO353_26575 - dihydropyrimidine dehydrogenase, at 5,819,582 to 5,820,949 _26575 AO353_26580: AO353_26580 - Dihydropyrimidine dehydrogenase (NADP(+)) (EC 1.3.1.2) (from data), at 5,820,950 to 5,822,224 _26580 AO353_26585: AO353_26585 - TetR family transcriptional regulator, at 5,822,347 to 5,822,967 _26585 AO353_26590: AO353_26590 - hypothetical protein, at 5,823,093 to 5,823,458 _26590 AO353_26595: AO353_26595 - copper resistance protein CopD, at 5,823,462 to 5,824,340 _26595 AO353_26600: AO353_26600 - disulfide bond formation protein DsbA, at 5,824,371 to 5,825,522 _26600 AO353_26605: AO353_26605 - MFS transporter, at 5,825,519 to 5,827,186 _26605
Locus Name Description Strand Phenotype
AO353_26555 AO353_26555 DHH family protein - insig.
AO353_26560 AO353_26560 Beta-ureidopropionase (EC 3.5.1.6) (from data) - strong
AO353_26565 AO353_26565 nitrate reductase - strong
AO353_26570 AO353_26570 Dihydropyrimidinase (EC 3.5.2.2) (from data) + strong
AO353_26575 AO353_26575 dihydropyrimidine dehydrogenase + strong
AO353_26580 AO353_26580 Dihydropyrimidine dehydrogenase (NADP(+)) (EC 1.3.1.2) (from data) + strong
AO353_26585 AO353_26585 TetR family transcriptional regulator - insig.
AO353_26590 AO353_26590 hypothetical protein + insig.
AO353_26595 AO353_26595 copper resistance protein CopD + sig.
AO353_26600 AO353_26600 disulfide bond formation protein DsbA - insig.
AO353_26605 AO353_26605 MFS transporter - insig.

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