Gene info for AO353_12250 in Pseudomonas fluorescens FW300-N2E3

Updated annotation (from data): Urocanate hydratase (EC 4.2.1.49)
Rationale: Specifically important for utilizing L-Histidine. Automated validation from mutant phenotype: the predicted function (UROCANATE-HYDRATASE-RXN) was linked to the condition via a MetaCyc pathway. This annotation was also checked manually.
Original annotation: urocanate hydratase
Type 1: Protein-coding gene
Located on scaffold CP012830, + strand, nucleotides 2,693,509 to 2,695,212
See nucleotide sequence around AO353_12250 or for all of scaffold CP012830

Other databases: NCBI, uniprot: A0A0N7H007

Nearby Genes

500 ntAO353_12225 and AO353_12230 are separated by 31 nucleotidesAO353_12230 and AO353_12235 are separated by 160 nucleotidesAO353_12235 and AO353_12240 are separated by 106 nucleotidesAO353_12240 and AO353_12245 are separated by 24 nucleotidesAO353_12245 and AO353_12250 are separated by 528 nucleotidesAO353_12250 and AO353_12255 are separated by 151 nucleotidesAO353_12255 and AO353_12260 are separated by 170 nucleotidesAO353_12260 and AO353_12265 overlap by 4 nucleotidesAO353_12265 and AO353_12270 are separated by 217 nucleotidesAO353_12270 and AO353_12275 are separated by 108 nucleotides AO353_12225: AO353_12225 - hypothetical protein, at 2,689,147 to 2,689,401 _12225 AO353_12230: AO353_12230 - lipocalin, at 2,689,433 to 2,690,002 _12230 AO353_12235: AO353_12235 - Formiminoglutamic iminohydrolase (EC 3.5.3.13) (from data), at 2,690,163 to 2,691,527 _12235 AO353_12240: AO353_12240 - histidine utilization repressor, at 2,691,634 to 2,692,383 _12240 AO353_12245: AO353_12245 - hypothetical protein, at 2,692,408 to 2,692,980 _12245 AO353_12250: AO353_12250 - Urocanate hydratase (EC 4.2.1.49) (from data), at 2,693,509 to 2,695,212 _12250 AO353_12255: AO353_12255 - sulfonate ABC transporter substrate-binding protein, at 2,695,364 to 2,696,830 _12255 AO353_12260: AO353_12260 - ABC transporter permease, at 2,697,001 to 2,697,852 _12260 AO353_12265: AO353_12265 - hypothetical protein, at 2,697,849 to 2,698,673 _12265 AO353_12270: AO353_12270 - histidine ammonia-lyase, at 2,698,891 to 2,700,423 _12270 AO353_12275: AO353_12275 - histidine permease (from data), at 2,700,532 to 2,701,938 _12275
Locus Name Description Strand Phenotype
AO353_12225 AO353_12225 hypothetical protein + insig.
AO353_12230 AO353_12230 lipocalin + insig.
AO353_12235 AO353_12235 Formiminoglutamic iminohydrolase (EC 3.5.3.13) (from data) - strong
AO353_12240 AO353_12240 histidine utilization repressor + strong
AO353_12245 AO353_12245 hypothetical protein + strong
AO353_12250 AO353_12250 Urocanate hydratase (EC 4.2.1.49) (from data) + strong
AO353_12255 AO353_12255 sulfonate ABC transporter substrate-binding protein + strong
AO353_12260 AO353_12260 ABC transporter permease + sig.
AO353_12265 AO353_12265 hypothetical protein + sig.
AO353_12270 AO353_12270 histidine ammonia-lyase + sig.
AO353_12275 AO353_12275 histidine permease (from data) + strong

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