Gene info for AO353_05970 in Pseudomonas fluorescens FW300-N2E3

Updated annotation (from data): Tryptophan 2,3-dioxygenase (EC 1.13.11.11)
Rationale: Specifically important for utilizing L-Tryptophan. Automated validation from mutant phenotype: the predicted function (RXN-8665) was linked to the condition via a MetaCyc pathway. This annotation was also checked manually.
Original annotation: tryptophan 2,3-dioxygenase
Type 1: Protein-coding gene
Located on scaffold CP012830, - strand, nucleotides 1,326,547 to 1,327,413
See nucleotide sequence around AO353_05970 or for all of scaffold CP012830

Other databases: NCBI, uniprot: A0A0N9WEI6

Nearby Genes

500 ntAO353_05945 and AO353_05950 are separated by 562 nucleotidesAO353_05950 and AO353_05955 are separated by 2 nucleotidesAO353_05955 and AO353_05960 are separated by 18 nucleotidesAO353_05960 and AO353_05965 are separated by 77 nucleotidesAO353_05965 and AO353_05970 are separated by 67 nucleotidesAO353_05970 and AO353_05975 overlap by 4 nucleotidesAO353_05975 and AO353_05980 are separated by 280 nucleotidesAO353_05980 and AO353_05985 are separated by 249 nucleotidesAO353_05985 and AO353_05990 are separated by 10 nucleotidesAO353_05990 and AO353_05995 are separated by 150 nucleotides AO353_05945: AO353_05945 - AraC family transcriptional regulator, at 1,320,502 to 1,321,515 _05945 AO353_05950: AO353_05950 - Anthranilate 1,2-dioxygenase (deaminating, decarboxylating) (EC 1.14.12.1) (from data), at 1,322,078 to 1,323,466 _05950 AO353_05955: AO353_05955 - Anthranilate 1,2-dioxygenase (deaminating, decarboxylating) (EC 1.14.12.1) (from data), at 1,323,469 to 1,323,960 _05955 AO353_05960: AO353_05960 - anthranilate dioxygenase reductase, at 1,323,979 to 1,325,001 _05960 AO353_05965: AO353_05965 - aromatic amino acid transporter, at 1,325,079 to 1,326,479 _05965 AO353_05970: AO353_05970 - Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (from data), at 1,326,547 to 1,327,413 _05970 AO353_05975: AO353_05975 - Kynurenine formamidase, bacterial (EC 3.5.1.9) (from data), at 1,327,410 to 1,328,075 _05975 AO353_05980: AO353_05980 - cupin, at 1,328,356 to 1,328,700 _05980 AO353_05985: AO353_05985 - 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data), at 1,328,950 to 1,329,834 _05985 AO353_05990: AO353_05990 - Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) (from data), at 1,329,845 to 1,331,368 _05990 AO353_05995: AO353_05995 - LysR family transcriptional regulator, at 1,331,519 to 1,332,466 _05995
Locus Name Description Strand Phenotype
AO353_05945 AO353_05945 AraC family transcriptional regulator - strong
AO353_05950 AO353_05950 Anthranilate 1,2-dioxygenase (deaminating, decarboxylating) (EC 1.14.12.1) (from data) + strong
AO353_05955 AO353_05955 Anthranilate 1,2-dioxygenase (deaminating, decarboxylating) (EC 1.14.12.1) (from data) + strong
AO353_05960 AO353_05960 anthranilate dioxygenase reductase + strong
AO353_05965 AO353_05965 aromatic amino acid transporter + sig.
AO353_05970 AO353_05970 Tryptophan 2,3-dioxygenase (EC 1.13.11.11) (from data) - strong
AO353_05975 AO353_05975 Kynurenine formamidase, bacterial (EC 3.5.1.9) (from data) - strong
AO353_05980 AO353_05980 cupin + strong
AO353_05985 AO353_05985 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) - strong
AO353_05990 AO353_05990 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) (from data) - strong
AO353_05995 AO353_05995 LysR family transcriptional regulator + strong

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