Gene info for Dshi_1649 in Dinoroseobacter shibae DFL-12

Updated annotation (from data): alpha-glucosidase / maltase / trehalase / sucrase (EC 3.2.1.48; EC 3.2.1.20; EC 3.2.1.28)
Rationale: Very important for fitness during growth on maltose, trehalose, or sucrose. 60% identical to Halomonas HaG, which is most active on maltose and sucrose and has some activity on trehalose (PMC3298133). Dshi_1649 is also important for utilization of glucose, which is not explained. The glucose phenotype is variable and might reflect polar effects on Dshi_1648, a component of the glucose/maltose/trehalose/sucrose transporter.
Original annotation: alpha amylase catalytic region (RefSeq)
Type 1: Protein-coding gene
Located on scaffold 57145, - strand, nucleotides 1,713,282 to 1,714,940
See nucleotide sequence around Dshi_1649 or for all of scaffold 57145

Other databases: MicrobesOnline, NCBI, IMG: 2501023519, uniprot: A8LLL3

Nearby Genes

500 ntDshi_1644 and Dshi_1645 are separated by 73 nucleotidesDshi_1645 and Dshi_1646 are separated by 3 nucleotidesDshi_1646 and Dshi_1647 are separated by 79 nucleotidesDshi_1647 and Dshi_1648 are separated by 274 nucleotidesDshi_1648 and Dshi_1649 are separated by 39 nucleotidesDshi_1649 and Dshi_1650 are separated by 13 nucleotidesDshi_1650 and Dshi_1651 are separated by 17 nucleotidesDshi_1651 and Dshi_1652 are separated by 72 nucleotidesDshi_1652 and Dshi_1653 are separated by 222 nucleotidesDshi_1653 and Dshi_1654 are separated by 9 nucleotides Dshi_1644: Dshi_1644 - integral membrane sensor hybrid histidine kinase (RefSeq), at 1,705,935 to 1,708,274 _1644 Dshi_1645: Dshi_1645 - Fmu (Sun) domain protein (RefSeq), at 1,708,348 to 1,709,526 _1645 Dshi_1646: Dshi_1646 - inosine-5'-monophosphate dehydrogenase (RefSeq), at 1,709,530 to 1,710,984 _1646 Dshi_1647: Dshi_1647 - 2-dehydro-3-deoxyglucarate aldolase (RefSeq), at 1,711,064 to 1,711,846 _1647 Dshi_1648: Dshi_1648 - glucose/maltose/trehalose/sucrose ABC transporter, ATPase component (from data), at 1,712,121 to 1,713,242 _1648 Dshi_1649: Dshi_1649 - alpha-glucosidase / maltase / trehalase / sucrase (EC 3.2.1.48; EC 3.2.1.20; EC 3.2.1.28) (from data), at 1,713,282 to 1,714,940 _1649 Dshi_1650: Dshi_1650 - glucose/maltose/trehalose/sucrose ABC transporter, permease component 2 (from data), at 1,714,954 to 1,716,111 _1650 Dshi_1651: Dshi_1651 - glucose/maltose/trehalose/sucrose ABC transporter, permease component 1 (from data), at 1,716,129 to 1,717,133 _1651 Dshi_1652: Dshi_1652 - glucose/maltose/trehalose/sucrose ABC transporter, substrate-binding component (from data), at 1,717,206 to 1,718,564 _1652 Dshi_1653: Dshi_1653 - transcriptional regulator, LacI family (RefSeq), at 1,718,787 to 1,719,851 _1653 Dshi_1654: Dshi_1654 - Beta-glucosidase (RefSeq), at 1,719,861 to 1,721,168 _1654
Locus Name Description Strand Phenotype
Dshi_1644 Dshi_1644 integral membrane sensor hybrid histidine kinase (RefSeq) - sig.
Dshi_1645 Dshi_1645 Fmu (Sun) domain protein (RefSeq) - sig.
Dshi_1646 Dshi_1646 inosine-5'-monophosphate dehydrogenase (RefSeq) - strong
Dshi_1647 Dshi_1647 2-dehydro-3-deoxyglucarate aldolase (RefSeq) - sig.
Dshi_1648 Dshi_1648 glucose/maltose/trehalose/sucrose ABC transporter, ATPase component (from data) - strong
Dshi_1649 Dshi_1649 alpha-glucosidase / maltase / trehalase / sucrase (EC 3.2.1.48; EC 3.2.1.20; EC 3.2.1.28) (from data) - strong
Dshi_1650 Dshi_1650 glucose/maltose/trehalose/sucrose ABC transporter, permease component 2 (from data) - strong
Dshi_1651 Dshi_1651 glucose/maltose/trehalose/sucrose ABC transporter, permease component 1 (from data) - strong
Dshi_1652 Dshi_1652 glucose/maltose/trehalose/sucrose ABC transporter, substrate-binding component (from data) - strong
Dshi_1653 Dshi_1653 transcriptional regulator, LacI family (RefSeq) + sig.
Dshi_1654 Dshi_1654 Beta-glucosidase (RefSeq) + insig.

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